日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ArgBP2γ interacts with Akt and p21-activated kinase-1 and promotes cell survival

ArgBP2γ 与 Akt 和 p21 激活激酶-1 相互作用,促进细胞存活

Yuan, Zeng-Qiang; Kim, Donghwa; Kaneko, Satoshi; Sussman, Melissa; Bokoch, Gary M; Kruh, Gary D; Nicosia, Santo V; Testa, Joseph R; Cheng, Jin Q

A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation

一种新型的Rac1 GAP剪接变体传递多聚泛素积累信号,从而介导Rac1失活。

Huang, Timothy Y; Michael, Sarah; Xu, Tao; Sarkeshik, Ali; Moresco, James J; Yates, John R 3rd; Masliah, Eliezer; Bokoch, Gary M; DerMardirossian, Céline

The microtubule-associated Rho activating factor GEF-H1 interacts with exocyst complex to regulate vesicle traffic

微管相关Rho激活因子GEF-H1与胞吐复合体相互作用,从而调节囊泡运输。

Pathak, Ritu; Delorme-Walker, Violaine D; Howell, Michael C; Anselmo, Anthony N; White, Michael A; Bokoch, Gary M; Dermardirossian, Céline

Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration

Pak1通过调节黏着斑强度、肌球蛋白IIA分布和肌动蛋白动力学来优化细胞迁移

Delorme-Walker, Violaine D; Peterson, Jeffrey R; Chernoff, Jonathan; Waterman, Clare M; Danuser, Gaudenz; DerMardirossian, Céline; Bokoch, Gary M

Direct interaction between Tks proteins and the N-terminal proline-rich region (PRR) of NoxA1 mediates Nox1-dependent ROS generation

Tks蛋白与NoxA1的N端富脯氨酸区(PRR)的直接相互作用介导Nox1依赖的活性氧(ROS)生成。

Gianni, Davide; DerMardirossian, Céline; Bokoch, Gary M

A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells.

一种新型的特异性 NADPH 氧化酶-1 (Nox1) 小分子抑制剂可阻断人类结肠癌细胞中功能性侵袭伪足的形成

Gianni Davide, Taulet Nicolas, Zhang Hui, DerMardirossian Celine, Kister Jeremy, Martinez Luis, Roush William R, Brown Steven J, Bokoch Gary M, Rosen Hugh

c-Src-mediated phosphorylation of NoxA1 and Tks4 induces the reactive oxygen species (ROS)-dependent formation of functional invadopodia in human colon cancer cells.

c-Src 介导的 NoxA1 和 Tks4 磷酸化诱导人类结肠癌细胞中活性氧 (ROS) 依赖的功能性侵袭伪足的形成

Gianni Davide, Taulet Nicolas, DerMardirossian Céline, Bokoch Gary M

Human neutrophils coordinate chemotaxis by differential activation of Rac1 and Rac2

人类中性粒细胞通过Rac1和Rac2的差异性激活来协调趋化作用。

Zhang, Hui; Sun, Chunxiang; Glogauer, Michael; Bokoch, Gary M

Inactivation of rho GTPases by statins attenuates anthrax lethal toxin activity

他汀类药物通过抑制Rho GTP酶活性来减弱炭疽致死毒素的活性。

deCathelineau, Aimee M; Bokoch, Gary M

Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edge

鸟嘌呤核苷酸交换因子-H1通过局部激活前缘的RhoA来调节细胞迁移。

Nalbant, Perihan; Chang, Yuan-Chen; Birkenfeld, Jörg; Chang, Zee-Fen; Bokoch, Gary M