Bolduc David M相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Discovery of Aminopyrazole Derivatives as Potent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR2 and 3

发现氨基吡唑衍生物是野生型和门控突变体FGFR2和3的有效抑制剂

期刊:ACS Medicinal Chemistry Letters

doi:10.1021/acsmedchemlett.0c00517

Brawn, Ryan A; Cook, Andrew; Omoto, Kiyoyuki; Ke, Jiyuan; Karr, Craig; Colombo, Federico; Virrankoski, Milena; Prajapati, Sudeep; Reynolds, Dominic; Bolduc, David M; Nguyen, Tuong-Vi; Gee, Patricia; Borrelli, Deanna; Caleb, Benjamin; Yao, Shihua; Irwin, Sean; Larsen, Nicholas A; Selvaraj, Anand; Zhao, Xuesong; Ioannidis, Stephanos

发表日期：2021

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Nicastrin functions to sterically hinder Î³-secretase-substrate interactions driven by substrate transmembrane domain.

Nicastrin 的作用是空间位阻，从而阻碍底物跨膜结构域驱动的 β-分泌酶-底物相互作用

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.1512952113

Bolduc David M, Montagna Daniel R, Gu Yongli, Selkoe Dennis J, Wolfe Michael S

空间多组学

发表日期：2016

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Structural basis of nSH2 regulation and lipid binding in PI3Kα

nSH2调控和PI3Kα脂质结合的结构基础

期刊:Oncotarget

doi:10.18632/oncotarget.2263

Miller, Michelle S; Schmidt-Kittler, Oleg; Bolduc, David M; Brower, Evan T; Chaves-Moreira, Daniele; Allaire, Marc; Kinzler, Kenneth W; Jennings, Ian G; Thompson, Philip E; Cole, Philip A; Amzel, L Mario; Vogelstein, Bert; Gabelli, Sandra B

发表日期：2014

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