日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
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2026
影响因子:
–

Lead optimization of an acylhydrazone scaffold possessing antiviral activity against Lassa virus

对具有抗拉沙病毒活性的酰腙骨架进行先导化合物优化

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2013.08.103
Burgeson, James R; Gharaibeh, Dima N; Moore, Amy L; Larson, Ryan A; Amberg, Sean M; Bolken, Tove' C; Hruby, Dennis E; Dai, Dongcheng
微生物学
发表日期：2013
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Safety and pharmacokinetics of the anti-orthopoxvirus compound ST-246 following a single daily oral dose for 14 days in human volunteers

在人体志愿者中，每日单次口服抗正痘病毒化合物ST-246，连续14天，其安全性和药代动力学研究

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00904-12
Chinsangaram, Jarasvech; Honeychurch, Kady M; Tyavanagimatt, Shanthakumar R; Leeds, Janet M; Bolken, Tove' C; Jones, Kevin F; Jordan, Robert; Marbury, Thomas; Ruckle, Jon; Mee-Lee, Denis; Ross, Eric; Lichtenstein, Israel; Pickens, Margaret; Corrado, Michael; Clarke, Jean M; Frimm, Annie M; Hruby, Dennis E
微生物学
发表日期：2012
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Pharmacokinetic comparison of a single oral dose of polymorph form i versus form V capsules of the antiorthopoxvirus compound ST-246 in human volunteers

在人体志愿者中比较单次口服抗正痘病毒化合物ST-246的多晶型i型胶囊与V型胶囊的药代动力学

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.06090-11
Chinsangaram, Jarasvech; Honeychurch, Kady M; Tyavanagimatt, Shanthakumar R; Bolken, Tove' C; Jordan, Robert; Jones, Kevin F; Marbury, Thomas; Lichtenstein, Israel; Pickens, Margaret; Corrado, Michael; Landis, Patrick; Clarke, Jean M; Frimm, Annie M; Hruby, Dennis E
微生物学
发表日期：2012
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Safety and pharmacokinetics of the antiorthopoxvirus compound ST-246 following repeat oral dosing in healthy adult subjects

健康成年受试者重复口服抗正痘病毒化合物ST-246后的安全性和药代动力学

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01689-09
Jordan, Robert; Chinsangaram, Jarasvech; Bolken, Tove' C; Tyavanagimatt, Shanthakumar R; Tien, Deborah; Jones, Kevin F; Frimm, Annie; Corrado, Michael L; Pickens, Margaret; Landis, Patrick; Clarke, Jean; Marbury, Thomas C; Hruby, Dennis E
微生物学
发表日期：2010
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Nonhuman primates are protected from smallpox virus or monkeypox virus challenges by the antiviral drug ST-246

非人灵长类动物可通过抗病毒药物ST-246免受天花病毒或猴痘病毒的攻击。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00021-09
Huggins, John; Goff, Arthur; Hensley, Lisa; Mucker, Eric; Shamblin, Josh; Wlazlowski, Carly; Johnson, Wendy; Chapman, Jennifer; Larsen, Tom; Twenhafel, Nancy; Karem, Kevin; Damon, Inger K; Byrd, Chelsea M; Bolken, Tove' C; Jordan, Robert; Hruby, Dennis
微生物学
猴痘
发表日期：2009
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Single-dose safety and pharmacokinetics of ST-246, a novel orthopoxvirus egress inhibitor

新型正痘病毒逸出抑制剂ST-246的单剂量安全性和药代动力学研究

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01303-07
Jordan, Robert; Tien, Deborah; Bolken, Tove' C; Jones, Kevin F; Tyavanagimatt, Shanthakumar R; Strasser, Josef; Frimm, Annie; Corrado, Michael L; Strome, Phoebe G; Hruby, Dennis E
微生物学
发表日期：2008
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Identification and characterization of potent small molecule inhibitor of hemorrhagic fever New World arenaviruses.

鉴定和表征出血热新世界沙粒病毒的强效小分子抑制剂

期刊:Antiviral Research
影响因子:4
doi:10.1016/j.antiviral.2005.10.008
Bolken Tove C, Laquerre Sylvie, Zhang Yuanming, Bailey Thomas R, Pevear Daniel C, Kickner Shirley S, Sperzel Lindsey E, Jones Kevin F, Warren Travis K, Amanda Lund S, Kirkwood-Watts Dana L, King David S, Shurtleff Amy C, Guttieri Mary C, Deng Yijun, Bleam Maureen, Hruby Dennis E
信号转导
发表日期：2006
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Molecular dissection of the vaccinia virus I7L core protein proteinase

痘苗病毒I7L核心蛋白蛋白酶的分子解剖

期刊:Journal of Virology
影响因子:3.8
doi:10.1128/jvi.77.20.11279-11283.2003
Byrd, Chelsea M; Bolken, Tove' C; Hruby, Dennis E
微生物学
发表日期：2003
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