Bolon Daniel N A相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Mutational scan of self-cleavage by HIV-1 protease provides new views of a conformationally dynamic mechanism

HIV-1蛋白酶自身切割的突变扫描为构象动态机制提供了新的视角

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/jvi.02229-25

Nachum, Gily S; Boucher, Jeffrey I; Flynn, Julia M; Quansah, Princess; Nachum, Sivan; Bolon, Daniel N A

发表日期：2026

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Dominant negative mutations in yeast Hsp90 indicate triage decision mechanism targeting client proteins for degradation.

酵母 Hsp90 中的显性负突变表明存在一种分流决策机制，该机制旨在将底物蛋白降解

期刊:Molecular Biology of the Cell

影响因子:2.7

doi:10.1091/mbc.E24-07-0309

Flynn Julia M, Joyce Margot E, Bolon Daniel N A

免疫/内分泌

发表日期：2025

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Mutational scan of self-cleavage by HIV-1 protease provides new views of a conformationally dynamic mechanism

HIV-1蛋白酶自身切割的突变扫描为构象动态机制提供了新的视角

doi:10.1101/2025.10.07.680924

Nachum, Gily S; Boucher, Jeffrey I; Flynn, Julia M; Quansah, Princess; Nachum, Sivan; Bolon, Daniel N A

发表日期：2025

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Contributions of Hyperactive Mutations in M(pro) from SARS-CoV-2 to Drug Resistance

SARS-CoV-2 M(pro) 蛋白高活性突变对耐药性的贡献

期刊:ACS Infectious Diseases

影响因子:3.8

doi:10.1021/acsinfecdis.3c00560

Flynn, Julia M; Zvornicanin, Sarah N; Tsepal, Tenzin; Shaqra, Ala M; Kurt Yilmaz, Nese; Jia, Weiping; Moquin, Stephanie; Dovala, Dustin; Schiffer, Celia A; Bolon, Daniel N A

发表日期：2024

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Dominant negative mutations in yeast Hsp90 reveal triage decision mechanism targeting client proteins for degradation.

酵母 Hsp90 中的显性负突变揭示了针对底物蛋白进行降解的分类决策机制

doi:10.1101/2024.01.02.573950

Flynn Julia M, Joyce Margot E, Bolon Daniel N A

免疫/内分泌

发表日期：2024

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Mutational fitness landscape and drug resistance

突变适应度景观与耐药性

期刊:Current Opinion in Structural Biology

doi:10.1016/j.sbi.2022.102525

Flynn, Julia; Samant, Neha; Schneider-Nachum, Gily; Tenzin, Tsepal; Bolon, Daniel N A

发表日期：2023

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Systematic Analyses of the Resistance Potential of Drugs Targeting SARS-CoV-2 Main Protease

对靶向SARS-CoV-2主蛋白酶的药物耐药潜力进行系统分析

期刊:ACS Infectious Diseases

影响因子:3.8

doi:10.1021/acsinfecdis.3c00125

Flynn, Julia M; Huang, Qiu Yu J; Zvornicanin, Sarah N; Schneider-Nachum, Gila; Shaqra, Ala M; Yilmaz, Nese Kurt; Moquin, Stephanie A; Dovala, Dustin; Schiffer, Celia A; Bolon, Daniel N A

发表日期：2023

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The Adaptive Potential of the Middle Domain of Yeast Hsp90

酵母Hsp90中间结构域的适应潜力

期刊:Molecular Biology and Evolution

影响因子:5.3

doi:10.1093/molbev/msaa211

Cote-Hammarlof, Pamela A; Fragata, Inês; Flynn, Julia; Mavor, David; Zeldovich, Konstantin B; Bank, Claudia; Bolon, Daniel N A

发表日期：2021

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Analyses of HIV proteases variants at the threshold of viability reveals relationships between processing efficiency and fitness

对处于存活阈值的HIV蛋白酶变体的分析揭示了加工效率与适应性之间的关系

期刊:Virus Evolution

doi:10.1093/ve/veab103

Schneider-Nachum, Gily; Flynn, Julia; Mavor, David; Schiffer, Celia A; Bolon, Daniel N A

发表日期：2021

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Constrained Mutational Sampling of Amino Acids in HIV-1 Protease Evolution

HIV-1蛋白酶进化中氨基酸的受限突变采样

期刊:Molecular Biology and Evolution

影响因子:5.3

doi:10.1093/molbev/msz022

Boucher, Jeffrey I; Whitfield, Troy W; Dauphin, Ann; Nachum, Gily; Hollins, Carl; Zeldovich, Konstantin B; Swanstrom, Ronald; Schiffer, Celia A; Luban, Jeremy; Bolon, Daniel N A

发表日期：2019

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