日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation-Induced Apoptosis.

BCL-XL 保护 ASS1 缺陷型癌细胞免受精氨酸饥饿诱导的细胞凋亡

Panda Prashanta Kumar, Paschoalini Mafra Ana Carolina, Bastos Alliny C S, Cao Li, Serra Bonet Maria, Brashears Caitlyn B, Chen Ethan Yang, Benedict-Hamilton Heather M, Ehrhardt William, Bomalaski John, Dehner Carina, Rogers Leonard C, Oyama Toshinao, Van Tine Brian A

Pegargiminase Plus First-Line Chemotherapy in Patients With Nonepithelioid Pleural Mesothelioma: The ATOMIC-Meso Randomized Clinical Trial

培加吉胺酶联合一线化疗治疗非上皮样胸膜间皮瘤患者:ATOMIC-Meso随机临床试验

Szlosarek, Peter W; Creelan, Benjamin C; Sarkodie, Thomas; Nolan, Luke; Taylor, Paul; Olevsky, Olga; Grosso, Federica; Cortinovis, Diego; Chitnis, Meenali; Roy, Amy; Gilligan, David; Kindler, Hedy; Papadatos-Pastos, Dionysis; Ceresoli, Giovanni L; Mansfield, Aaron S; Tsao, Anne; O'Byrne, Kenneth J; Nowak, Anna K; Steele, Jeremy; Sheaff, Michael; Shiu, Chiung-Fang; Kuo, Chih-Ling; Johnston, Amanda; Bomalaski, John; Zauderer, Marjorie G; Fennell, Dean A

Arginine deprivation/citrulline augmentation with ADI-PEG20 as novel therapy for complications in type 2 diabetes

使用 ADI-PEG20 进行精氨酸剥夺/瓜氨酸增加作为 2 型糖尿病并发症的新疗法

Ammar A Abdelrahman, Porsche V Sandow, Jing Wang, Zhimin Xu, Modesto Rojas, John S Bomalaski, Tahira Lemtalsi, Ruth B Caldwell, Robert W Caldwell

Overcoming resistance to arginine deprivation therapy using GC7 in pleural mesothelioma

使用 GC7 克服胸膜间皮瘤对精氨酸剥夺疗法的抵抗力

Josephine Carpentier, Marta Freitas, Valle Morales, Katiuscia Bianchi, John Bomalaski, Peter Szlosarek, Sarah A Martin

Discovery and Targeting of a Noncanonical Mechanism of Sarcoma Resistance to ADI-PEG20 Mediated by the Microenvironment

发现并靶向微环境介导的肉瘤对 ADI-PEG20 产生耐药性的非典型机制

Leonard C Rogers, Jeff C Kremer, Caitlyn B Brashears, Zongtao Lin, Zhixian Hu, Alliny C S Bastos, Adriana Baker, Nicole Fettig, Dong Zhou, Kooresh I Shoghi, Carina A Dehner, John S A Chrisinger, John S Bomalaski, Benjamin A Garcia, Toshinao Oyama, Eileen P White, Brian A Van Tine

A role for macrophages under cytokine control in mediating resistance to ADI-PEG20 (pegargiminase) in ASS1-deficient mesothelioma

巨噬细胞在细胞因子控制下介导 ASS1 缺陷型间皮瘤对 ADI-PEG20(培根酰胺酶)的耐药性

Melissa M Phillips #, Iuliia Pavlyk #, Michael Allen, Essam Ghazaly, Rosalind Cutts, Josephine Carpentier, Joe Scott Berry, Callum Nattress, Shenghui Feng, Gunnel Hallden, Claude Chelala, John Bomalaski, Jeremy Steele, Michael Sheaff, Frances Balkwill, Peter W Szlosarek

Pegylated arginine deiminase drives arginine turnover and systemic autophagy to dictate energy metabolism

聚乙二醇化精氨酸脱亚胺酶驱动精氨酸周转和系统自噬来决定能量代谢

Yiming Zhang, Cassandra B Higgins, Brian A Van Tine, John S Bomalaski, Brian J DeBosch

Pilot Trial of Arginine Deprivation Plus Nivolumab and Ipilimumab in Patients with Metastatic Uveal Melanoma.

精氨酸剥夺联合纳武利尤单抗和伊匹木单抗治疗转移性葡萄膜黑色素瘤患者的试点试验

Kraehenbuehl Lukas, Holland Aliya, Armstrong Emma, O'Shea Sirinya, Mangarin Levi, Chekalil Sara, Johnston Amanda, Bomalaski John S, Erinjeri Joseph P, Barker Christopher A, Francis Jasmine H, Wolchok Jedd D, Merghoub Taha, Shoushtari Alexander N

Role of 3'-Deoxy-3'-[(18)F] Fluorothymidine Positron Emission Tomography-Computed Tomography as a Predictive Biomarker in Argininosuccinate Synthetase 1-Deficient Thoracic Cancers Treated With Pegargiminase

3'-脱氧-3'-[(18)F]氟胸苷正电子发射断层扫描-计算机断层扫描作为精氨酸琥珀酸合成酶1缺陷型胸部肿瘤经培加吉明酶治疗的预测性生物标志物的作用

Szyszko, Teresa A; Dunn, Joel T; Phillips, Melissa M; Bomalaski, John; Sheaff, Michael T; Ellis, Steve; Pike, Lucy; Goh, Vicky; Cook, Gary J R; Szlosarek, Peter W

Phase 1 trial of ADI-PEG 20 and liposomal doxorubicin in patients with metastatic solid tumors

ADI-PEG 20 和脂质体阿霉素治疗转移性实体瘤患者的 1 期临床试验

Yao, Shuyang; Janku, Filip; Koenig, Kimberly; Tsimberidou, Apostolia Maria; Piha-Paul, Sarina Anne; Shi, Nai; Stewart, John; Johnston, Amanda; Bomalaski, John; Meric-Bernstam, Funda; Fu, Siqing