日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation-Induced Apoptosis.

BCL-XL 保护 ASS1 缺陷型癌细胞免受精氨酸饥饿诱导的细胞凋亡

Panda Prashanta Kumar, Paschoalini Mafra Ana Carolina, Bastos Alliny C S, Cao Li, Serra Bonet Maria, Brashears Caitlyn B, Chen Ethan Yang, Benedict-Hamilton Heather M, Ehrhardt William, Bomalaski John, Dehner Carina, Rogers Leonard C, Oyama Toshinao, Van Tine Brian A

Pegargiminase Plus First-Line Chemotherapy in Patients With Nonepithelioid Pleural Mesothelioma: The ATOMIC-Meso Randomized Clinical Trial

培加吉胺酶联合一线化疗治疗非上皮样胸膜间皮瘤患者:ATOMIC-Meso随机临床试验

Szlosarek, Peter W; Creelan, Benjamin C; Sarkodie, Thomas; Nolan, Luke; Taylor, Paul; Olevsky, Olga; Grosso, Federica; Cortinovis, Diego; Chitnis, Meenali; Roy, Amy; Gilligan, David; Kindler, Hedy; Papadatos-Pastos, Dionysis; Ceresoli, Giovanni L; Mansfield, Aaron S; Tsao, Anne; O'Byrne, Kenneth J; Nowak, Anna K; Steele, Jeremy; Sheaff, Michael; Shiu, Chiung-Fang; Kuo, Chih-Ling; Johnston, Amanda; Bomalaski, John; Zauderer, Marjorie G; Fennell, Dean A

Pilot Trial of Arginine Deprivation Plus Nivolumab and Ipilimumab in Patients with Metastatic Uveal Melanoma.

精氨酸剥夺联合纳武利尤单抗和伊匹木单抗治疗转移性葡萄膜黑色素瘤患者的试点试验

Kraehenbuehl Lukas, Holland Aliya, Armstrong Emma, O'Shea Sirinya, Mangarin Levi, Chekalil Sara, Johnston Amanda, Bomalaski John S, Erinjeri Joseph P, Barker Christopher A, Francis Jasmine H, Wolchok Jedd D, Merghoub Taha, Shoushtari Alexander N

Role of 3'-Deoxy-3'-[(18)F] Fluorothymidine Positron Emission Tomography-Computed Tomography as a Predictive Biomarker in Argininosuccinate Synthetase 1-Deficient Thoracic Cancers Treated With Pegargiminase

3'-脱氧-3'-[(18)F]氟胸苷正电子发射断层扫描-计算机断层扫描作为精氨酸琥珀酸合成酶1缺陷型胸部肿瘤经培加吉明酶治疗的预测性生物标志物的作用

Szyszko, Teresa A; Dunn, Joel T; Phillips, Melissa M; Bomalaski, John; Sheaff, Michael T; Ellis, Steve; Pike, Lucy; Goh, Vicky; Cook, Gary J R; Szlosarek, Peter W

Phase 1 trial of ADI-PEG 20 and liposomal doxorubicin in patients with metastatic solid tumors

ADI-PEG 20 和脂质体阿霉素治疗转移性实体瘤患者的 1 期临床试验

Yao, Shuyang; Janku, Filip; Koenig, Kimberly; Tsimberidou, Apostolia Maria; Piha-Paul, Sarina Anne; Shi, Nai; Stewart, John; Johnston, Amanda; Bomalaski, John; Meric-Bernstam, Funda; Fu, Siqing

A Phase 1 study of ADI-PEG20 (pegargiminase) combined with cisplatin and pemetrexed in ASS1-negative metastatic uveal melanoma

一项针对ASS1阴性转移性葡萄膜黑色素瘤的ADI-PEG20(培加吉胺酶)联合顺铂和培美曲塞的I期研究

Chan, Pui Ying; Phillips, Melissa M; Ellis, Stephen; Johnston, Amanda; Feng, Xiaoxing; Arora, Amit; Hay, Gordon; Cohen, Victoria M L; Sagoo, Mandeep S; Bomalaski, John S; Sheaff, Michael T; Szlosarek, Peter W

Phase 1 trial of ADI-PEG20 plus cisplatin in patients with pretreated metastatic melanoma or other advanced solid malignancies

ADI-PEG20联合顺铂治疗既往接受过治疗的转移性黑色素瘤或其他晚期实体恶性肿瘤患者的I期临床试验

Yao, Shuyang; Janku, Filip; Subbiah, Vivek; Stewart, John; Patel, Sapna Pradyuman; Kaseb, Ahmed; Westin, Shannon Neville; Naing, Aung; Tsimberidou, Apostolia Maria; Hong, David; Piha-Paul, Sarina Anne; Shi, Nai; Johnston, Amanda; Bomalaski, John; Fu, Siqing

Phase 1b study of pegylated arginine deiminase (ADI-PEG 20) plus Pembrolizumab in advanced solid cancers

聚乙二醇化精氨酸脱亚胺酶(ADI-PEG 20)联合帕博利珠单抗治疗晚期实体瘤的1b期研究

Chang, Kwang-Yu; Chiang, Nai-Jung; Wu, Shang-Yin; Yen, Chia-Jui; Chen, Shang-Hung; Yeh, Yu-Min; Li, Chien-Feng; Feng, Xiaoxing; Wu, Katherine; Johnston, Amanda; Bomalaski, John S; Wu, Bor-Wen; Gao, Jianjun; Subudhi, Sumit K; Kaseb, Ahmed O; Blando, Jorge M; Yadav, Shalini S; Szlosarek, Peter W; Chen, Li-Tzong

Assessment of pegylated arginine deiminase and modified FOLFOX6 in patients with advanced hepatocellular carcinoma: Results of an international, single-arm, phase 2 study

评估聚乙二醇化精氨酸脱亚胺酶和改良FOLFOX6方案在晚期肝细胞癌患者中的疗效:一项国际单臂II期研究的结果

Harding, James J; Yang, Tsai-Sheng; Chen, Yen-Yang; Feng, Yin-Hsun; Yen, Chia-Jui; Ho, Ching-Liang; Huang, Wen-Tsung; El Dika, Imane; Akce, Mehmet; Tan, Benjamin; Cohen, Stacey A; Meyer, Timothy; Sarker, Debashis; Lee, Dae-Won; Ryoo, Baek-Yeol; Lim, Ho Yeong; Johnston, Amanda; Bomalaski, John S; O'Reilly, Eileen M; Qin, Shukui; Abou-Alfa, Ghassan K

Phase I study of ADI-PEG20 plus low-dose cytarabine for the treatment of acute myeloid leukemia

ADI-PEG20联合低剂量阿糖胞苷治疗急性髓系白血病的I期研究

Tsai, Hui-Jen; Hsiao, Hui-Hua; Hsu, Ya-Ting; Liu, Yi-Chang; Kao, Hsiao-Wen; Liu, Ta-Chih; Cho, Shih-Feng; Feng, Xiaoxing; Johnston, Amanda; Bomalaski, John S; Kuo, Ming-Chung; Chen, Tsai-Yun