日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Na(V)1.5 or K(Ca)2 channel blockade does not increase arrhythmia risk in hypokalemic rabbit hearts, unlike K(V)11.1 inhibition with dofetilide.

与多非利特抑制 K(V)11.1 不同,Na(V)1.5 或 K(Ca)2 通道阻滞不会增加低钾血症兔心脏的心律失常风险

Yan Yannan, Abildgaard Lea, Skarsfeldt Mark Alexander, Bomholtz Sofia Hammami, Sørensen Ulrik, Holst Anders Gaarsdal, Grunnet Morten, Diness Jonas Goldin, Bentzen Bo Hjorth

Novel human neurodevelopmental and neurodegenerative disease associated with IRF2BPL gene variants-mechanisms and therapeutic avenues

与IRF2BPL基因变异相关的新型人类神经发育和神经退行性疾病——机制和治疗途径

Bauersachs, Daniel; Bomholtz, Louise; Del Rey Mateos, Sara; Kühn, Ralf; Lisowski, Pawel

A Bacteriophage Cocktail Significantly Reduces Listeria monocytogenes without Deleterious Impact on the Commensal Gut Microbiota under Simulated Gastrointestinal Conditions

噬菌体混合物可显著减少单核细胞增生李斯特菌,而不会在模拟胃肠道条件下对共生肠道菌群造成有害影响

Rasmus Riemer Jakobsen, Jimmy T Trinh, Louise Bomholtz, Signe Kristine Brok-Lauridsen, Alexander Sulakvelidze, Dennis Sandris Nielsen

Whole-Exome Sequencing Implicates Neuronal Calcium Channel with Familial Atrial Fibrillation

全外显子组测序揭示神经元钙通道与家族性房颤有关

Vad, Oliver Bundgaard; Yan, Yannan; Denti, Federico; Ahlberg, Gustav; Refsgaard, Lena; Bomholtz, Sofia Hammami; Santos, Joana Larupa; Rasmussen, Simon; Haunsø, Stig; Svendsen, Jesper Hastrup; Christophersen, Ingrid Elizabeth; Schmitt, Nicole; Olesen, Morten Salling; Bentzen, Bo Hjorth

Mechanisms of Action of the KCa2-Negative Modulator AP30663, a Novel Compound in Development for Treatment of Atrial Fibrillation in Man

KCa2负调控剂AP30663的作用机制:一种正在研发用于治疗人类心房颤动的新型化合物

Bentzen, Bo Hjorth; Bomholtz, Sofia Hammami; Simó-Vicens, Rafel; Folkersen, Lasse; Abildgaard, Lea; Speerschneider, Tobias; Muthukumarasamy, Kalai Mangai; Edvardsson, Nils; Sørensen, Ulrik S; Grunnet, Morten; Diness, Jonas Goldin

Inhibition of K(Ca)2 Channels Decreased the Risk of Ventricular Arrhythmia in the Guinea Pig Heart During Induced Hypokalemia.

抑制 K(Ca)2 通道可降低豚鼠心脏在诱发低钾血症期间发生室性心律失常的风险

Diness Jonas Goldin, Abildgaard Lea, Bomholtz Sofia Hammami, Skarsfeldt Mark Alexander, Edvardsson Nils, Sørensen Ulrik S, Grunnet Morten, Bentzen Bo Hjorth

The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

KCa2 通道抑制剂 AP14145(而非多非利特或昂丹司琼)可为豚鼠心脏提供功能性心房选择性

Jeppe Egedal Kirchhoff, Mark Alexander Skarsfeldt, Kalai Mangai Muthukumarasamy, Rafel Simó-Vicens, Sofia Hammami Bomholtz, Lea Abildgaard, Thomas Jespersen, Ulrik S Sørensen, Morten Grunnet, Bo Hjorth Bentzen, Jonas Goldin Diness

Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

通过抑制猪小电导 Ca2+ 激活 K+ 通道终止维纳卡兰耐药性心房颤动

Jonas Goldin Diness, Lasse Skibsbye, Rafel Simó-Vicens, Joana Larupa Santos, Pia Lundegaard, Carlotta Citerni, Daniel Rafael Peter Sauter, Sofia Hammami Bomholtz, Jesper Hastrup Svendsen, Søren-Peter Olesen, Ulrik S Sørensen, Thomas Jespersen, Morten Grunnet, Bo Hjorth Bentzen

Cell volume changes regulate slick (Slo2.1), but not slack (Slo2.2) K+ channels

细胞体积变化调节光滑型(Slo2.1)钾离子通道,但不调节松弛型(Slo2.2)钾离子通道。

Tejada, Maria A; Stople, Kathleen; Hammami Bomholtz, Sofia; Meinild, Anne-Kristine; Poulsen, Asser Nyander; Klaerke, Dan A

A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein

磷酸肌醇 3-激酶 (PI3K)-血清和糖皮质激素诱导激酶 1 (SGK1) 通路通过抑制 Nedd4-2 蛋白促进 Kv7.1 通道表面表达

Martin Nybo Andersen, Katarzyna Krzystanek, Frederic Petersen, Sofia Hammami Bomholtz, Søren-Peter Olesen, Hugues Abriel, Thomas Jespersen, Hanne Borger Rasmussen