Bommineni Gopal R相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase

吡啶酮和二苯醚类抑制剂对鼠疫耶尔森菌FabV烯酰-ACP还原酶的选择性

期刊:Biochemistry

doi:10.1021/acs.biochem.5b01301

Neckles, Carla; Pschibul, Annica; Lai, Cheng-Tsung; Hirschbeck, Maria; Kuper, Jochen; Davoodi, Shabnam; Zou, Junjie; Liu, Nina; Pan, Pan; Shah, Sonam; Daryaee, Fereidoon; Bommineni, Gopal R; Lai, Cristina; Simmerling, Carlos; Kisker, Caroline; Tonge, Peter J

发表日期：2016

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Substituted diphenyl ethers as a novel chemotherapeutic platform against Burkholderia pseudomallei

取代二苯醚作为对抗类鼻疽伯克霍尔德菌的新型化学治疗平台

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.02296-13

Cummings, Jason E; Beaupre, Adam J; Knudson, Susan E; Liu, Nina; Yu, Weixuan; Neckles, Carla; Wang, Hui; Khanna, Avinash; Bommineni, Gopal R; Trunck, Lily A; Schweizer, Herbert P; Tonge, Peter J; Slayden, Richard A

发表日期：2014

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Rational design of broad spectrum antibacterial activity based on a clinically relevant enoyl-acyl carrier protein (ACP) reductase inhibitor.

基于临床相关的烯酰-酰基载体蛋白（ACP）还原酶抑制剂的广谱抗菌活性的合理设计

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M113.532804

Schiebel Johannes, Chang Andrew, Shah Sonam, Lu Yang, Liu Li, Pan Pan, Hirschbeck Maria W, Tareilus Mona, Eltschkner Sandra, Yu Weixuan, Cummings Jason E, Knudson Susan E, Bommineni Gopal R, Walker Stephen G, Slayden Richard A, Sotriffer Christoph A, Tonge Peter J, Kisker Caroline

免疫/内分泌

发表日期：2014

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A structural and energetic model for the slow-onset inhibition of the Mycobacterium tuberculosis enoyl-ACP reductase InhA

结核分枝杆菌烯酰-ACP还原酶InhA缓慢抑制的结构和能量模型

期刊:ACS Chemical Biology

影响因子:3.8

doi:10.1021/cb400896g

Li, Huei-Jiun; Lai, Cheng-Tsung; Pan, Pan; Yu, Weixuan; Liu, Nina; Bommineni, Gopal R; Garcia-Diaz, Miguel; Simmerling, Carlos; Tonge, Peter J

发表日期：2014

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Time-dependent diaryl ether inhibitors of InhA: structure-activity relationship studies of enzyme inhibition, antibacterial activity, and in vivo efficacy

InhA 的时间依赖性二芳醚抑制剂：酶抑制、抗菌活性和体内疗效的构效关系研究

期刊:ChemMedChem

影响因子:3.4

doi:10.1002/cmdc.201300429

Pan, Pan; Knudson, Susan E; Bommineni, Gopal R; Li, Huei-Jiun; Lai, Cheng-Tsung; Liu, Nina; Garcia-Diaz, Miguel; Simmerling, Carlos; Patil, Sachindra S; Slayden, Richard A; Tonge, Peter J

发表日期：2014

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Structural basis for the recognition of mycolic acid precursors by KasA, a condensing enzyme and drug target from Mycobacterium tuberculosis

结核分枝杆菌缩合酶和药物靶点 KasA 识别分枝菌酸前体的结构基础

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M113.511436

Schiebel, Johannes; Kapilashrami, Kanishk; Fekete, Agnes; Bommineni, Gopal R; Schaefer, Christin M; Mueller, Martin J; Tonge, Peter J; Kisker, Caroline

发表日期：2013

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The Francisella tularensis FabI enoyl-acyl carrier protein reductase gene is essential to bacterial viability and is expressed during infection

土拉弗朗西斯菌FabI烯酰-酰基载体蛋白还原酶基因对细菌的存活至关重要，并在感染过程中表达。

期刊:Journal of Bacteriology

doi:10.1128/JB.01957-12

Kingry, Luke C; Cummings, Jason E; Brookman, Kerry W; Bommineni, Gopal R; Tonge, Peter J; Slayden, Richard A

发表日期：2013

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Rational optimization of drug-target residence time: insights from inhibitor binding to the Staphylococcus aureus FabI enzyme-product complex.

合理优化药物靶点停留时间：从抑制剂与金黄色葡萄球菌 FabI 酶-产物复合物的结合中获得的启示

期刊:Biochemistry

doi:10.1021/bi400413c

Chang Andrew, Schiebel Johannes, Yu Weixuan, Bommineni Gopal R, Pan Pan, Baxter Michael V, Khanna Avinash, Sotriffer Christoph A, Kisker Caroline, Tonge Peter J

发表日期：2013

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Slow onset inhibition of bacterial beta-ketoacyl-acyl carrier protein synthases by thiolactomycin

硫代乳酸霉素对细菌β-酮酰基-酰基载体蛋白合成酶的缓慢抑制作用

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M109.077909

Machutta, Carl A; Bommineni, Gopal R; Luckner, Sylvia R; Kapilashrami, Kanishk; Ruzsicska, Bela; Simmerling, Carlos; Kisker, Caroline; Tonge, Peter J

发表日期：2010

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