日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Patterns of response in head and neck cancer subregions using daily Quantitative MRI from MR-guided radiation therapy

利用每日定量磁共振成像技术分析头颈癌亚区域的磁共振引导放射治疗反应模式

Bonate, Ryan; Awan, Musaddiq; Himburg, Heather; Wong, Stuart; Shukla, Monica; Zenga, Joseph; Paulson, Eric S

A Multiple-Model-Informed Drug-Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab

基于多模型指导的溶瘤病毒联合帕博利珠单抗最佳治疗方案选择药物开发方法

Yamada, Akihiro; Choules, Mary P; Brightman, Frances A; Takeshita, Shigeru; Nakao, Shinsuke; Amino, Nobuaki; Nakayama, Takeshi; Takeuchi, Masato; Komatsu, Kanji; Ortega, Fernando; Mistry, Hitesh; Orrell, David; Chassagnole, Christophe; Bonate, Peter L

Population PK and Exposure-Response Analyses of Zolbetuximab in Patients With Locally Advanced Unresectable or Metastatic G/GEJ Adenocarcinoma

佐贝妥昔单抗治疗局部晚期不可切除或转移性胃/胃食管交界处腺癌患者的群体药代动力学和暴露-反应分析

Yamada, Akihiro; Takeuchi, Masato; Komatsu, Kanji; Bonate, Peter L; Poondru, Srinivasu; Yang, Jianning

In Vitro Evaluation of CYP-Mediated Metabolism of Fezolinetant and Pharmacokinetic Interaction Between Fezolinetant and Fluvoxamine in Healthy Postmenopausal Smokers and Nonsmokers

体外评价菲唑利坦的CYP介导代谢以及菲唑利坦与氟伏沙明在健康绝经后吸烟者和非吸烟者中的药代动力学相互作用

Iwai, Megumi; Nielsen, Jace; Miyagawa, Mayuko; Patton, Melanie; Bonate, Peter L; Wang, Xuegong; Wojtkowski, Tomasz; Sinn, Angela; Huang, Jiayin

Population pharmacokinetic analysis of fluorouracil and oxaliplatin in the absence or presence of zolbetuximab in locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma

在局部晚期不可切除或转移性胃癌或胃食管交界处腺癌中,氟尿嘧啶和奥沙利铂在有或无佐贝妥昔单抗治疗下的群体药代动力学分析

Yamada, Akihiro; Yang, Jianning; Bonate, Peter L; Heo, Nakyo; Poondru, Srinivasu

Clinical Pharmacology of the Antibody-Drug Conjugate Enfortumab Vedotin in Advanced Urothelial Carcinoma and Other Malignant Solid Tumors

抗体药物偶联物恩福妥单抗在晚期尿路上皮癌和其他恶性实体瘤中的临床药理学研究

Tang, Mei; Garg, Amit; Bonate, Peter L; Rosenberg, Jonathan E; Matsangou, Maria; Kadokura, Takeshi; Yamada, Akihiro; Choules, Mary; Pavese, Janet; Nagata, Masanori; Tenmizu, Daisuke; Koibuchi, Akira; Heo, Nakyo; Wang, Lu; Wojtkowski, Tomasz; Hanley, William D; Poondru, Srinivasu

Enhancing inclusivity in clinical trials: Model-informed drug development for pregnant individuals in the era of personalized medicine

增强临床试验的包容性:在个性化医疗时代,基于模型指导的孕妇药物研发

Dallmann, André; Bonate, Peter L; Burnham, Janelle; George, Blessy; Yao, Lynne; Knöchel, Jane

Prospective approaches to gene therapy computational modeling - spotlight on viral gene therapy

基因治疗计算建模的前瞻性方法——聚焦病毒基因治疗

Choules, Mary P; Bonate, Peter L; Heo, Nakyo; Weddell, Jared

A comprehensive regulatory and industry review of modeling and simulation practices in oncology clinical drug development

对肿瘤临床药物研发中建模和仿真实践进行全面的监管和行业审查

Ruiz-Garcia, Ana; Baverel, Paul; Bottino, Dean; Dolton, Michael; Feng, Yan; González-García, Ignacio; Kim, Jaeyeon; Robey, Seth; Singh, Indrajeet; Turner, David; Wu, Shu-Pei; Yin, Donghua; Zhou, Di; Zhu, Hao; Bonate, Peter

Phosphodiesterase 10A (PDE10A): Regulator of Dopamine Agonist-Induced Gene Expression in the Striatum

磷酸二酯酶10A (PDE10A):纹状体中多巴胺激动剂诱导基因表达的调节因子

Bonate, Ryan; Kurek, Gabriela; Hrabak, Michael; Patterson, Santanna; Padovan-Neto, Fernando; West, Anthony R; Steiner, Heinz