日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Perivascular brain clearance as a therapeutic target in cerebral amyloid angiopathy and Alzheimer's disease

脑血管周围清除作为脑淀粉样血管病和阿尔茨海默病的一种治疗靶点

Bonnar, Orla; Eyre, Beth; van Veluw, Susanne J

APOE4 and sedentary lifestyle synergistically impair neurovascular function in the visual cortex of awake mice

APOE4基因和久坐的生活方式协同作用,损害清醒小鼠视觉皮层的神经血管功能。

Anderle, Silvia; Bonnar, Orla; Henderson, Joseph; Shaw, Kira; Chagas, Andre M; McMullan, Letitia; Webber, Alexandra; McGowan, Kirsty; King, Sarah L; Hall, Catherine N

Implementation of Piperacillin-Tazobactam Continuous Infusions for Critically Ill Patients: A Single-Centre Retrospective Chart Review

哌拉西林-他唑巴坦持续输注治疗危重患者的实施情况:单中心回顾性病历分析

Landry, Kylie; MacKenzie, Meghan; Burgess, Sarah; Bonnar, Paul; Shabi, Yahya; Patriquin, Glenn; Holland, Karolynn; Eichhorn, Volker

A beginner's guide to implementation science

实施科学入门指南

de Waard, Dominique; Gainer, Ryan; Sim, Meaghan; Cote, Claudia; Tremblay, Philippe; Bonnar, Paul; Hirsch, Gregory

APOE4 expression confers a mild, persistent reduction in neurovascular function in the visual cortex and hippocampus of awake mice

APOE4表达会导致清醒小鼠视觉皮层和海马的神经血管功能轻微且持续性降低。

Bonnar, Orla; Shaw, Kira; Anderle, Silvia; Grijseels, Dori M; Clarke, Devin; Bell, Laura; King, Sarah L; Hall, Catherine N

Spontaneous vasomotion propagates along pial arterioles in the awake mouse brain like stimulus-evoked vascular reactivity

在清醒的小鼠大脑中,自发性血管运动沿软脑膜小动脉传播,类似于刺激诱发的血管反应性。

Munting, Leon P; Bonnar, Orla; Kozberg, Mariel G; Auger, Corinne A; Hirschler, Lydiane; Hou, Steven S; Greenberg, Steven M; Bacskai, Brian J; van Veluw, Susanne J

Systematic review of the method and quality of reporting of complications from studies evaluating innovative glaucoma surgical procedures

对评估创新型青光眼手术方案的研究中并发症报告的方法和质量进行系统评价

Bonnar, Jonathan; Azuara-Blanco, Augusto

Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq

利用基因组规模的扰动测序技术绘制信息丰富的基因型-表型图谱

Joseph M Replogle ,Reuben A Saunders ,Angela N Pogson ,Jeffrey A Hussmann ,Alexander Lenail ,Alina Guna ,Lauren Mascibroda ,Eric J Wagner ,Karen Adelman ,Gila Lithwick-Yanai ,Nika Iremadze ,Florian Oberstrass ,Doron Lipson ,Jessica L Bonnar ,Marco Jost ,Thomas M Norman ,Jonathan S Weissman

Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors

利用双sgRNA文库和最佳效应分子最大限度地提高CRISPRi的效率和可及性

Joseph M Replogle # ,Jessica L Bonnar # ,Angela N Pogson # ,Christina R Liem ,Nolan K Maier ,Yufang Ding ,Baylee J Russell ,Xingren Wang ,Kun Leng ,Alina Guna ,Thomas M Norman ,Ryan A Pak ,Daniel M Ramos ,Michael E Ward ,Luke A Gilbert ,Martin Kampmann ,Jonathan S Weissman ,Marco Jost

Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages

神经胶质细胞表型的变化先于明显的神经原纤维缠结形成,与皮质细胞损伤标志物相关,并可预测 Braak III-IV 期个体的认知状态

Raquel N Taddei, Maria V Sanchez-Mico, Orla Bonnar, Theresa Connors, Angelica Gaona, Dominique Denbow, Matthew P Frosch, Teresa Gómez-Isla