日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tissue and extracellular matrix remodeling of the subchondral bone during osteoarthritis of knee joints as revealed by spatial mass spectrometry imaging

空间质谱成像揭示膝关节骨关节炎过程中软骨下骨的组织和细胞外基质重塑

Schurman, Charles A; Bons, Joanna; Woo, Jonathon J; Yee, Cristal; Liu, Qi; Tao, Nannan; Alliston, Tamara; Angel, Peggi; Schilling, Birgit

Concerted changes in Epithelium and Stroma: a multi-scale, multi-omics analysis of progression from Barrett's Esophagus to adenocarcinoma

上皮和间质的协同变化:从巴雷特食管到腺癌进展的多尺度、多组学分析

Strasser, Michael K; Gibbs, David L; Gascard, Philippe; Bons, Joanna; Hickey, John W; Pan, Deng; Caruso, Joseph A; Wang, Xianhong; Chen-Tanyolac, Chira; Bai, Rosemary; Schürch, Christian M; Tan, Yuqi; Black, Sarah; Chu, Pauline; Ozkan, Alican; Basisty, Nathan; Sangwan, Veena; Rose, Jacob; Shah, Samah; Burton, Jordan B; Camilleri-Broet, Sophie; Fiset, Pierre Olivier; Bertos, Nicholas; Berube, Julie; Djambazian, Haig; Li, Rui; Oikonomopoulos, Spyridon; Elliott, Daffolyn Rachael Fels; Vernovsky, Sarah; Shimshoni, Elee; Collyar, Deborah; Russell, Ann; Ragoussis, Jiannis; Stachler, Matthew D; Goldenring, James R; McDonald, Stuart A C; Ingber, Donald E; Schilling, Birgit; Nolan, Garry P; Tlsty, Thea D; Huang, Sui; Ferri, Lorenzo E

Loss of long-chain acyl-CoA dehydrogenase protects against acute kidney injury.

长链酰基辅酶A脱氢酶的缺失可预防急性肾损伤

Chiba Takuto, Oda Akira, Zhang Yuxun, Pfister Katherine, Bons Joanna, Bharathi Sivakama S, Kinoshita Ayako, Zhang Bob B, Richert Adam, Schilling Birgit, Goetzman Eric, Sims-Lucas Sunder

Substrate stiffness dictates unique doxorubicin-induced senescence-associated secretory phenotypes and transcriptomic signatures in human pulmonary fibroblasts.

基质硬度决定了人类肺成纤维细胞中独特的阿霉素诱导衰老相关分泌表型和转录组特征

Du Huixun, Rose Jacob P, Bons Joanna, Guo Li, Valentino Taylor R, Wu Fei, Burton Jordan B, Basisty Nathan, Manwaring-Mueller Max, Makhijani Priya, Chen Nan, Chang Veronica, Winer Shawn, Campisi Judith, Furman David, Nagy Andras, Schilling Birgit, Winer Daniel A

Inhibition of the metalloprotease ADAM19 as a novel senomorphic strategy to ameliorate gut permeability and senescence markers by modulating senescence-associated secretory phenotype (SASP).

抑制金属蛋白酶 ADAM19 是一种新型的衰老策略,通过调节衰老相关分泌表型 (SASP) 来改善肠道通透性和衰老标志物

Bar Sudipta, Hilsabeck Tyler A U, Pattavina Blaine, López-Domínguez José Alberto, Basisty Nathan, Bons Joanna, Watson Mark, Schilling Birgit, Campisi Judith, Kapahi Pankaj, Sharma Amit

Exosomes released from senescent cells and circulatory exosomes isolated from human plasma reveal aging-associated proteomic and lipid signatures.

衰老细胞释放的外泌体和从人血浆中分离的循环外泌体揭示了与衰老相关的蛋白质组学和脂质特征

Patel Sandip Kumar, Bons Joanna, Rose Jacob P, Chappel Jessie R, Beres Rebecca L, Watson Mark A, Webster Corey, Burton Jordan B, Bruderer Roland, Desprez Pierre-Yves, Reiter Lukas, Campisi Judith, Baker Erin S, Schilling Birgit

Tissue and Extracellular Matrix Remodeling of the Subchondral Bone during Osteoarthritis of Knee Joints as revealed by Spatial Mass Spectrometry Imaging

空间质谱成像揭示膝关节骨关节炎过程中软骨下骨的组织和细胞外基质重塑

Schurman, Charles A; Bons, Joanna; Woo, Jonathon J; Yee, Cristal; Tao, Nannan; Alliston, Tamara; Angel, Peggi; Schilling, Birgit

Multiplexed Targeted Spatial Mass Spectrometry Imaging Assays to monitor lipids and NAD(+) metabolites in CD38 knockout mice exhibiting improved metabolism.

多重靶向空间质谱成像分析法监测 CD38 敲除小鼠体内脂质和 NAD(+) 代谢物,该小鼠表现出代谢改善

Schilling Birgit, Schurman Charles, Bons Joanna, Kumaar Prasanna, Fang Jingji, Roberts Andrea, Hormazabal Genesis, Riley Rebeccah, Tao Nannan, Verdin Eric

A multi-omics analysis of human fibroblasts overexpressing an Alu transposon reveals widespread disruptions in aging-associated pathways.

对过度表达 Alu 转座子的人类成纤维细胞进行多组学分析,揭示了衰老相关通路的广泛紊乱

Bravo Juan I, Tewelde Eyael, King Christina D, Bons Joanna, Shah Samah, Rose Jacob, Campisi Judith, Schilling Birgit, Benayoun Bérénice A

Aging impairs the osteocytic regulation of collagen integrity and bone quality

衰老会损害骨细胞对胶原蛋白完整性和骨骼质量的调节能力。

Schurman, Charles A; Kaya, Serra; Dole, Neha; Luna, Nadja M Maldonado; Castillo, Natalia; Potter, Ryan; Rose, Jacob P; Bons, Joanna; King, Christina D; Burton, Jordan B; Schilling, Birgit; Melov, Simon; Tang, Simon; Schaible, Eric; Alliston, Tamara