日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Butyrate histone deacetylase inhibitors

丁酸组蛋白去乙酰化酶抑制剂

Steliou, Kosta; Boosalis, Michael S; Perrine, Susan P; Sangerman, José; Faller, Douglas V

Erythroid Kruppel-like factor (EKLF) is recruited to the gamma-globin gene promoter as a co-activator and is required for gamma-globin gene induction by short-chain fatty acid derivatives

红细胞 Kruppel 样因子 (EKLF) 作为共激活因子被募集到 γ-珠蛋白基因启动子上,是短链脂肪酸衍生物诱导 γ-珠蛋白基因表达所必需的。

Perrine, Susan P; Mankidy, Rishikesh; Boosalis, Michael S; Bieker, James J; Faller, Douglas V

Short-chain fatty acids induce gamma-globin gene expression by displacement of a HDAC3-NCoR repressor complex

短链脂肪酸通过置换 HDAC3-NCoR 抑制复合物来诱导 γ-珠蛋白基因表达。

Mankidy, Rishikesh; Faller, Douglas V; Mabaera, Rodwell; Lowrey, Christopher H; Boosalis, Michael S; White, Gary L; Castaneda, Serguei A; Perrine, Susan P

Identification of novel small-molecule inducers of fetal hemoglobin using pharmacophore and 'PSEUDO' receptor models

利用药效团和“伪”受体模型鉴定新型胎儿血红蛋白小分子诱导剂

Bohacek, Regine; Boosalis, Michael S; McMartin, Colin; Faller, Douglas V; Perrine, Susan P

Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo.

短链脂肪酸衍生物可诱导胎儿珠蛋白表达和体内红细胞生成

Pace Betty S, White Gary L, Dover George J, Boosalis Michael S, Faller Douglas V, Perrine Susan P