Bormans相关文献与解析，生知库 | 链接生命科学的每一步

Leekens, Simon; Casteels, Peter; Van Bogaert, Tom; Deschaght, Pieter; De Brabandere, Veronique; Cawthorne, Christopher; Bormans, Guy; Cleeren, Frederik

发表日期：2026

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HDAC6 inhibitors sensitize resistant t(11;14) multiple myeloma cells to a combination of bortezomib and BH3 mimetics

HDAC6抑制剂可使耐药的t(11;14)多发性骨髓瘤细胞对硼替佐米和BH3模拟物联合疗法敏感。

期刊:Haematologica

影响因子:7.9

doi:10.3324/haematol.2024.286279

Florean, Cristina; Lernoux, Manon; Lorant, Anne; Losson, Helene; Bormans, Guy; Schnekenburger, Michael; Diederich, Marc

Selective PET imaging of CXCR4 using the Al(18)F-labeled antagonist LY2510924

使用 Al(18)F 标记的拮抗剂 LY2510924 对 CXCR4 进行选择性 PET 成像

期刊:European Journal of Nuclear Medicine and Molecular Imaging

影响因子:7.6

doi:10.1007/s00259-024-07025-w

Spahn, Muriel Aline; Loy, Tom Van; Celen, Sofie; Koole, Michel; Deroose, Christophe M; Cawthorne, Christopher; Vanduffel, Wim; Schols, Dominique; Bormans, Guy; Cleeren, Frederik

CXCR4

发表日期：2025

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Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein.

通过与髓鞘少突胶质细胞糖蛋白（一种中枢神经系统特异性蛋白）的额外结合，延长抗体在大脑中的半衰期

期刊:Fluids and Barriers of the Cns

影响因子:6.2

doi:10.1186/s12987-025-00624-1

Cuypers Marie-Lynn, Jaspers Tom, Clerckx Jarne, Leekens Simon, Cawthorne Christopher, Bormans Guy, Cleeren Frederik, Geukens Nick, De Strooper Bart, Dewilde Maarten

Real-Time Monitoring of the Formation and Culture of Hybrid Cell-Microbiomaterial Spheroids Using Non-Faradaic Electrical Impedance Spectroscopy

利用非法拉第电阻抗谱法实时监测混合细胞-微生物材料球体的形成和培养

期刊:ACS Biomaterials Science & Engineering

影响因子:5.5

doi:10.1021/acsbiomaterials.5c00402

Fois, Maria G; Bormans, Seppe; Vandenryt, Thijs; Guttenplan, Alexander P M; Alaoui Selsouli, Yousra; van Blitterswijk, Clemens; Tahmasebi Birgani, Zeinab; Giselbrecht, Stefan; Habibović, Pamela; Thoelen, Ronald; Truckenmüller, Roman K

Development and evaluation of Hsp90-targeting nanobodies for visualisation of extracellular Hsp90 in tumours using PET imaging

开发和评估针对 Hsp90 的纳米抗体，以使用 PET 成像可视化肿瘤中的细胞外 Hsp90

期刊:EJNMMI Radiopharmacy and Chemistry

影响因子:4.4

doi:10.1186/s41181-025-00331-0

Valeria Narykina, Janke Kleynhans, Christopher Cawthorne, Joost Schymkowitz, Frederic Rousseau, Guy Bormans

Martinostat as a novel HDAC inhibitor to overcome tyrosine kinase inhibitor resistance in chronic myeloid leukemia.

Martinostat 是一种新型 HDAC 抑制剂，可克服慢性粒细胞白血病中的酪氨酸激酶抑制剂耐药性

期刊:Clinical Epigenetics

影响因子:4.4

doi:10.1186/s13148-025-01921-0

Yang Haeun, Li Vladimir, Park Su Jung, Cheon Sang Won, Lorant Anne, Mazumder Aloran, Lee Jin Young, Orlikova-Boyer Barbora, Cerella Claudia, Christov Christo, Kirsch Gilbert, Olberg Dag Erlend, Bormans Guy, Kang Hyoung Jin, Han Byung Woo, Schnekenburger Michael, Diederich Marc

[(11)C]HSP990 PET as a translational tool to investigate the role of Hsp90 in tumours and support the development of Hsp90 therapeutics.

[(11)C]HSP990 PET 作为转化工具，用于研究 Hsp90 在肿瘤中的作用，并支持 Hsp90 疗法的开发。

期刊:EJNMMI Radiopharmacy and Chemistry

影响因子:3.3

doi:10.1186/s41181-025-00386-z

Cools Romy, Narykina Valeria, Vermeulen Koen, Mishra Sanket J, Blagg Brian S J, Derweduwe Marleen, De Smet Frederik, Ziani-Zeryouh Aaron, Riva Matteo, Coosemans An, Rousseau Frederic, Schymkowitz Joost, Bormans Guy

In vivo imaging of heat shock protein 90: Diagnostic tool and support for Hsp90-targeted therapy

热休克蛋白90的体内成像：诊断工具及Hsp90靶向治疗的支持

期刊:Cell Stress & Chaperones

影响因子:3.2

doi:10.1016/j.cstres.2025.100105

Cools, Romy; Vermeulen, Koen; Bormans, Guy

发表日期：2025

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Experience in a PTEN Hamartoma Tumor Syndrome Expertise Centre: Yield of Thyroid Ultrasound Surveillance in Children with PTEN Hamartoma Tumor Syndrome

PTEN错构瘤肿瘤综合征专科中心经验：甲状腺超声监测在PTEN错构瘤肿瘤综合征患儿中的应用价值

期刊:Journal of Clinical Research in Pediatric Endocrinology

影响因子:1.5

doi:10.4274/jcrpe.galenos.2024.2024-3-14

Bormans, Esther M G; Schuurs-Hoeijmakers, Janneke H M; van Setten, Petra; Hendricks, Linda A J; Drissen, Meggie M C M; Gotthardt, Martin; Claahsen-van der Grinten, Hedi L; Hoogerbrugge, Nicoline; Schieving, Jolanda H

Affinity- and Format-Dependent Pharmacokinetics of (89)Zr-Labeled Albumin-Binding VHH Constructs

亲和力和形式依赖性的(89)Zr标记白蛋白结合VHH构建体的药代动力学

HDAC6 inhibitors sensitize resistant t(11;14) multiple myeloma cells to a combination of bortezomib and BH3 mimetics

HDAC6抑制剂可使耐药的t(11;14)多发性骨髓瘤细胞对硼替佐米和BH3模拟物联合疗法敏感。

Selective PET imaging of CXCR4 using the Al(18)F-labeled antagonist LY2510924

使用 Al(18)F 标记的拮抗剂 LY2510924 对 CXCR4 进行选择性 PET 成像

Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein.

通过与髓鞘少突胶质细胞糖蛋白（一种中枢神经系统特异性蛋白）的额外结合，延长抗体在大脑中的半衰期

Real-Time Monitoring of the Formation and Culture of Hybrid Cell-Microbiomaterial Spheroids Using Non-Faradaic Electrical Impedance Spectroscopy

利用非法拉第电阻抗谱法实时监测混合细胞-微生物材料球体的形成和培养

Development and evaluation of Hsp90-targeting nanobodies for visualisation of extracellular Hsp90 in tumours using PET imaging

开发和评估针对 Hsp90 的纳米抗体，以使用 PET 成像可视化肿瘤中的细胞外 Hsp90

Martinostat as a novel HDAC inhibitor to overcome tyrosine kinase inhibitor resistance in chronic myeloid leukemia.

Martinostat 是一种新型 HDAC 抑制剂，可克服慢性粒细胞白血病中的酪氨酸激酶抑制剂耐药性

[(11)C]HSP990 PET as a translational tool to investigate the role of Hsp90 in tumours and support the development of Hsp90 therapeutics.

[(11)C]HSP990 PET 作为转化工具，用于研究 Hsp90 在肿瘤中的作用，并支持 Hsp90 疗法的开发。

In vivo imaging of heat shock protein 90: Diagnostic tool and support for Hsp90-targeted therapy

热休克蛋白90的体内成像：诊断工具及Hsp90靶向治疗的支持

Experience in a PTEN Hamartoma Tumor Syndrome Expertise Centre: Yield of Thyroid Ultrasound Surveillance in Children with PTEN Hamartoma Tumor Syndrome

PTEN错构瘤肿瘤综合征专科中心经验：甲状腺超声监测在PTEN错构瘤肿瘤综合征患儿中的应用价值