日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

GIPR signaling modulates PYY-induced hypophagia and malaise in rodents

GIPR信号通路调节啮齿动物中PYY诱导的食欲减退和不适感

Borner, Tito; Pataro, Allison M; Curtis, Genevieve R; Alonso, Brandon; Hu, Jiayin; Fortin, Samantha M; Koul-Tiwari, Richa; Hughes, Emily; Kong, Jimmy X; Jordan, Emily; Barnes, Robert; Bernardo, Barbara; Gardner, Maxwell; Ma, Wenzhe; Gosset, James R; Esquejo, Ryan M; Fortin, Jean-Philippe; De Jonghe, Bart C; Bence, Kendra K; Hayes, Matthew R

GLP-1R biased cAMP agonism maintains glycemic control with reduced malaise and emesis in preclinical mammalian models

在临床前哺乳动物模型中,GLP-1R 偏向性 cAMP 激动剂作用可维持血糖控制,并减少不适和呕吐。

Baumer-Harrison, Caitlin; Aldaghma, Danya; White, Alex D; Applebey, Sarah V; Pataro, Allison M; Mohiby, Allaha Z; Alonso, Brandon; Xiao, Allison G; O'Farrell, Libbey S; Qian, Yuewei; Coskun, Tamer; Coghlan, Matthew P; Willard, Francis S; Ai, Minrong; Sloop, Kyle W; Doyle, Robert P; Borner, Tito; De Jonghe, Bart C; Hayes, Matthew R

GLP-1 at the Metabolic-Cognitive Interface: Reward, Affect, and Memory

GLP-1在代谢-认知界面中的作用:奖赏、情感和记忆

Gao, Serena X; Décarie-Spain, Léa; Gu, Cindy; Mazzini, Giulia; Kanoski, Scott E; Borner, Tito

Hindbrain octadecaneuropeptide gliotransmission as a therapeutic target for energy balance control without nausea or emesis

后脑十八肽神经胶质传递作为能量平衡控制的治疗靶点,不引起恶心或呕吐

Geisler, Caroline E; Chichura, Kylie S; Orativskyi, Oleksandr; Hu, Jiayin; Belser, Drew L; Pelletier, Caitlyn M; Borner, Tito; Baumer-Harrison, Caitlin; De Jonghe, Bart C; Crist, Richard C; Reiner, Benjamin C; Doyle, Robert P; Hayes, Matthew R

Hypophagia and body weight loss by tirzepatide are accompanied by fewer GI adverse events compared to semaglutide in preclinical models.

在临床前模型中,与司美格鲁肽相比,替拉帕肽引起的食欲减退和体重减轻伴随的胃肠道不良事件较少

Borner Tito, Pataro Allison M, Doebley Sarah A, Furst Charles D, White Alex D, Gao Serena X, Chow Angela, Sanchez-Navarro Marcos J, Ghidewon Misgana Y, Halas Julia G, Mohiby Allaha Z, Willard Francis S, Grill Harvey J, Ai Minrong, Samms Ricardo J, Hayes Matthew R, De Jonghe Bart C

Central mechanisms of emesis: A role for GDF15

呕吐的中枢机制:GDF15 的作用

Borner, Tito; Pataro, Allison M; De Jonghe, Bart C

The antiemetic actions of GIP receptor agonism

GIP受体激动剂的止吐作用

Borner, Tito; De Jonghe, Bart C; Hayes, Matthew R

GIP receptor agonism blocks chemotherapy-induced nausea and vomiting

GIP受体激动剂可阻断化疗引起的恶心和呕吐

Borner, Tito; Reiner, Benjamin C; Crist, Richard C; Furst, C Daniel; Doebley, Sarah A; Halas, Julia G; Ai, Minrong; Samms, Ricardo J; De Jonghe, Bart C; Hayes, Matthew R

Novel Insights into the Physiology of Nutrient Sensing and Gut-Brain Communication in Surgical and Experimental Obesity Therapy

外科和实验性肥胖治疗中营养感知和肠脑通讯生理学的新见解

Frick, Lukas D; Hankir, Mohammed K; Borner, Tito; Malagola, Ermanno; File, Bálint; Gero, Daniel

Single nuclei RNA sequencing of the rat AP and NTS following GDF15 treatment

GDF15治疗后大鼠AP和NTS的单核RNA测序

Reiner, Benjamin C; Crist, Richard C; Borner, Tito; Doyle, Robert P; Hayes, Matthew R; De Jonghe, Bart C