日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Molecular determinants of phase separation for Drosophila DNA replication licensing factors

果蝇 DNA 复制许可因子相分离的分子决定因素

Matthew W Parker #, Jonchee A Kao #, Alvin Huang #, James M Berger, Michael R Botchan

Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome

真核复制体的 CMG 解旋酶进行 ATP 水解驱动的 DNA 易位的分子基础

Patrik Eickhoff, Hazal B Kose, Fabrizio Martino, Tatjana Petojevic, Ferdos Abid Ali, Julia Locke, Nele Tamberg, Andrea Nans, James M Berger, Michael R Botchan, Hasan Yardimci, Alessandro Costa

A new class of disordered elements controls DNA replication through initiator self-assembly

一类新的无序元素通过引发剂自组装控制 DNA 复制

Matthew W Parker, Maren Bell, Mustafa Mir, Jonchee A Kao, Xavier Darzacq, Michael R Botchan, James M Berger

Conformational control and DNA-binding mechanism of the metazoan origin recognition complex

后生动物起源识别复合物的构象控制和DNA结合机制

Bleichert, Franziska; Leitner, Alexander; Aebersold, Ruedi; Botchan, Michael R; Berger, James M

Mechanisms and regulation of DNA replication initiation in eukaryotes

真核生物DNA复制起始的机制和调控

Parker, Matthew W; Botchan, Michael R; Berger, James M

A rare variant in the FHL1 gene associated with X-linked recessive hypoparathyroidism

FHL1基因的一种罕见变异与X连锁隐性甲状旁腺功能减退症相关

Pillar, Nir; Pleniceanu, Oren; Fang, Mingyan; Ziv, Limor; Lahav, Einat; Botchan, Shay; Cheng, Le; Dekel, Benjamin; Shomron, Noam

Crystal structure of the eukaryotic origin recognition complex

真核生物起源识别复合物的晶体结构

Bleichert, Franziska; Botchan, Michael R; Berger, James M

Biotechnology. A prudent path forward for genomic engineering and germline gene modification

生物技术。基因组工程和生殖系基因改造的明智发展之路

David Baltimore, Paul Berg, Michael Botchan, Dana Carroll, R Alta Charo, George Church, Jacob E Corn, George Q Daley, Jennifer A Doudna, Marsha Fenner, Henry T Greely, Martin Jinek, G Steven Martin, Edward Penhoet, Jennifer Puck, Samuel H Sternberg, Jonathan S Weissman, Keith R Yamamoto

Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement

Cdc45(细胞分裂周期蛋白45)守护着真核生物复制体解旋酶的入口,稳定前导链的结合。

Petojevic, Tatjana; Pesavento, James J; Costa, Alessandro; Liang, Jingdan; Wang, Zhijun; Berger, James M; Botchan, Michael R

Actionable clinical decisions based on comprehensive genomic evaluation in asymptomatic adults

基于对无症状成年人进行全面基因组评估的可操作临床决策

Pillar, Nir; Isakov, Ofer; Weissglas-Volkov, Daphna; Botchan, Shay; Friedman, Eitan; Arber, Nadir; Shomron, Noam