日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Crowding-induced opening of the mechanosensitive Piezo1 channel in silico

计算机模拟中拥挤诱导的机械敏感型 Piezo1 通道开放

Jiang, Wenjuan; Del Rosario, John Smith; Botello-Smith, Wesley; Zhao, Siyuan; Lin, Yi-Chun; Zhang, Han; Lacroix, Jérôme; Rohacs, Tibor; Luo, Yun Lyna

Free energy and kinetics of cAMP permeation through connexin26 via applied voltage and milestoning

通过施加电压和里程碑事件研究 cAMP 通过连接蛋白 26 渗透的自由能和动力学

Jiang, Wenjuan; Lin, Yi-Chun; Botello-Smith, Wesley; Contreras, Jorge E; Harris, Andrew L; Maragliano, Luca; Luo, Yun Lyna

In silico prediction of ARB resistance: A first step in creating personalized ARB therapy

利用计算机模拟预测ARB耐药性:创建个性化ARB治疗的第一步

Anderson, Shane D; Tabassum, Asna; Yeon, Jae Kyung; Sharma, Garima; Santos, Priscilla; Soong, Tik Hang; Thu, Yin Win; Nies, Isaac; Kurita, Tomomi; Chandler, Andrew; Alsamarah, Abdelaziz; Kanassatega, Rhye-Samuel; Luo, Yun L; Botello-Smith, Wesley M; Andresen, Bradley T

A mechanism for the activation of the mechanosensitive Piezo1 channel by the small molecule Yoda1

小分子 Yoda1 激活机械敏感的 Piezo1 通道的机制

Wesley M Botello-Smith, Wenjuan Jiang, Han Zhang, Alper D Ozkan, Yi-Chun Lin, Christine N Pham, Jérôme J Lacroix, Yun Luo

The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening

人类连接蛋白26的N14K突变会破坏胞质亚基间的相互作用,并促进通道开放。

Valdez Capuccino, Juan M; Chatterjee, Payal; García, Isaac E; Botello-Smith, Wesley M; Zhang, Han; Harris, Andrew L; Luo, Yun; Contreras, Jorge E

Probing the gating mechanism of the mechanosensitive channel Piezo1 with the small molecule Yoda1

利用小分子 Yoda1 探索机械敏感通道 Piezo1 的门控机制

Jerome J Lacroix, Wesley M Botello-Smith, Yun Luo

Can Relative Binding Free Energy Predict Selectivity of Reversible Covalent Inhibitors?

相对结合自由能能否预测可逆共价抑制剂的选择性?

Chatterjee, Payal; Botello-Smith, Wesley M; Zhang, Han; Qian, Li; Alsamarah, Abdelaziz; Kent, David; Lacroix, Jerome J; Baudry, Michel; Luo, Yun

Acceleration of Linear Finite-Difference Poisson-Boltzmann Methods on Graphics Processing Units

在图形处理器上加速线性有限差分泊松-玻尔兹曼方法

Qi, Ruxi; Botello-Smith, Wesley M; Luo, Ray