日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Design, synthesis and cytotoxic research of a novel antitumor model based on acrylamide-PABA analogs via β-tubulin inhibition

基于丙烯酰胺-PABA类似物通过β-微管蛋白抑制作用构建新型抗肿瘤模型的设计、合成及细胞毒性研究

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d5ra02384j
Alghamdi, Maha Ali; Abdulbaqi, Mustafa R; Alshaya, Dalal Sulaiman; Alharthi, Jawaher; Katouah, Hanadi A; Elsaid, Fahmy Gad; Fayad, Eman; Abu Almaaty, Ali H; Abdullah Alzahrani, Abdullah Yahya; Beshay, Botros Y
细胞生物学
肿瘤
毒理研究
肿瘤免疫
发表日期：2025
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Evaluating the structure-based virtual screening performance of SARS-CoV-2 main protease: A benchmarking approach and a multistage screening example against the wild-type and Omicron variants

评估基于结构的SARS-CoV-2主蛋白酶虚拟筛选性能：基准测试方法和针对野生型和Omicron变体的多阶段筛选示例

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0318712
Galal, Noha; Beshay, Botros Y; Soliman, Omar; Ismail, Muhammad I; Abdelfadil, Mohamed; El-Hadidi, Mohamed; Arafa, Reem K; Ibrahim, Tamer M
SARS-CoV-2
发表日期：2025
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'Poly phenolic phytoceutical loaded nano-bilosomes for enhanced caco-2 cell permeability and SARS-CoV 2 antiviral activity': in-vitro and insilico studies

“负载多酚类植物药的纳米脂质体增强Caco-2细胞通透性和SARS-CoV-2抗病毒活性”：体外和计算机模拟研究

期刊:Drug Delivery
影响因子:8.1
doi:10.1080/10717544.2022.2162157
Zakaria, Mohamed Y; Abd El-Halim, Shady M; Beshay, Botros Y; Zaki, Islam; Abourehab, Mohammed A S
微生物学
SARS-CoV-2
细胞生物学
发表日期：2023
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Design, synthesis, anti-inflammatory evaluation, and molecular modelling of new coumarin-based analogs combined curcumin and other heterocycles as potential TNF-α production inhibitors via upregulating Nrf2/HO-1, downregulating AKT/mTOR signalling pathways and downregulating NF-κB in LPS induced macrophages

设计、合成、抗炎评价和分子建模新型香豆素类似物，将姜黄素与其他杂环化合物结合，作为潜在的TNF-α产生抑制剂，通过上调Nrf2/HO-1、下调AKT/mTOR信号通路和下调LPS诱导的巨噬细胞中的NF-κB发挥作用。

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2023.2243551
Ghany, Lina M A Abdel; Beshay, Botros Y; Youssef Moustafa, Amal M; Maghrabi, Ali Hassan Ahmed; Ali, Eman Hussain Khalifa; Saleem, Rasha Mohammed; Zaki, Islam; Ryad, Noha
巨噬细胞
mTOR
巨噬细胞
信号转导
NF-κB
TNF-α
细胞生物学
AKT
免疫/内分泌
发表日期：2023
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Design, synthesis and antiproliferative screening of newly synthesized coumarin-acrylamide hybrids as potential cytotoxic and apoptosis inducing agents

设计、合成并筛选新型香豆素-丙烯酰胺杂合物作为潜在的细胞毒性和凋亡诱导剂的抗增殖活性

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d3ra06644d
Abd El-Lateef, Hany M; Abdel Ghany, Lina M A; Saleem, Rasha Mohammed; Ahmed Maghrabi, Ali Hassan; Yahya Alahdal, Maryam Abdulrahman; Khalifa Ali, Eman Hussain; Beshay, Botros Y; Zaki, Islam; Masoud, Reham E
细胞生物学
凋亡
毒理研究
表观遗传
发表日期：2023
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Novel Acrylate-Based Derivatives: Design, Synthesis, Antiproliferative Screening, and Docking Study as Potential Combretastatin Analogues

新型丙烯酸酯类衍生物：设计、合成、抗增殖筛选和分子对接研究及其作为潜在的康布瑞他汀类似物的应用

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.3c05051
Fayad, Eman; Altalhi, Sarah Awwadh; Abualnaja, Matokah M; Alrohaimi, Abdulmohsen H; Elsaid, Fahmy G; Abu Almaaty, Ali H; Saleem, Rasha Mohammed; Bazuhair, Mohammed A; Ahmed Maghrabi, Ali Hassan; Beshay, Botros Y; Zaki, Islam
发表日期：2023
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Biological activities and biosorption potential of red algae (Corallina officinalis) to remove toxic malachite green dye

红藻（Corallina officinalis）去除有毒孔雀石绿染料的生物活性和生物吸附潜力

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-023-40667-8
Youssef, Elen Emad; Beshay, Botros Y; Tonbol, Kareem; Makled, Sarah O
发表日期：2023
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Design and synthesis of new trimethoxylphenyl-linked combretastatin analogues loaded on diamond nanoparticles as a panel for ameliorated solubility and antiproliferative activity

设计和合成新型三甲氧基苯基连接的考布他汀类似物，将其负载于金刚石纳米粒子上，作为改善溶解度和抗增殖活性的面板

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.6
doi:10.1080/14756366.2022.2116016
Islam Zaki, Amal M Y Moustafa, Botros Y Beshay, Reham E Masoud, Mohammed A I Elbastawesy, Mohammed A S Abourehab, Mohamed Y Zakaria
信号转导
发表日期：2022
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Inclusion of a Phytomedicinal Flavonoid in Biocompatible Surface-Modified Chylomicron Mimic Nanovesicles with Improved Oral Bioavailability and Virucidal Activity: Molecular Modeling and Pharmacodynamic Studies

将植物药黄酮类化合物纳入生物相容性表面改性乳糜微粒模拟纳米囊泡中，以提高口服生物利用度和杀病毒活性：分子建模和药效学研究

期刊:Pharmaceutics
影响因子:4.9
doi:10.3390/pharmaceutics14050905
Mohamed Y Zakaria, Paris E Georghiou, Joseph H Banoub, Botros Y Beshay
免疫
微生物学
发表日期：2022
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Design, Green Synthesis and Tailoring of Vitamin E TPGS Augmented Niosomal Nano-Carrier of Pyrazolopyrimidines as Potential Anti-Liver and Breast Cancer Agents with Accentuated Oral Bioavailability

维生素 E TPGS 增强型吡唑并嘧啶类脂质体纳米载体的设计、绿色合成和定制，作为具有增强口服生物利用度的潜在抗肝癌和乳腺癌药物

期刊:Pharmaceuticals
影响因子:
doi:10.3390/ph15030330
Kurls E Anwer, Nour E A Abd El-Sattar, Marium M Shamaa, Mohamed Y Zakaria, Botros Y Beshay
肿瘤
乳腺癌
肝癌
发表日期：2022
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