日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Potential Molecular Targets of the Broad-Range Antimicrobial Peptide Tyrothricin in the Apicomplexan Parasite Toxoplasma gondii

弓形虫（Toxoplasma gondii）中广谱抗菌肽酪菌素的潜在分子靶点

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines14010172
Amdouni, Yosra; Boubaker, Ghalia; Müller, Joachim; Sousa, Maria Cristina Ferreira de; Hänggeli, Kai Pascal Alexander; Uldry, Anne-Christine; Braga-Lagache, Sophie; Heller, Manfred; Hemphill, Andrew
发表日期：2026
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In Vivo Safety and Efficacy of Thiosemicarbazones in Experimental Mice Infected with Toxoplasma gondii Oocysts.

硫代氨基脲类药物在感染弓形虫卵囊的实验小鼠体内的安全性和有效性

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines13081879
Semeraro Manuela, Boubaker Ghalia, Scaccaglia Mirco, Imhof Dennis, de Sousa Maria Cristina Ferreira, Hänggeli Kai Pascal Alexander, Löwe Anitha, Genchi Marco, Kramer Laura Helen, Vismarra Alice, Pelosi Giorgio, Bisceglie Franco, Ortega-Mora Luis Miguel, Müller Joachim, Hemphill Andrew
炎症/感染
发表日期：2025
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Loss of NcBPK1 impairs bradyzoite differentiation and enhances virulence in Neospora caninum

NcBPK1 的缺失会损害缓殖子的分化并增强犬新孢子虫的毒力。

期刊:Parasites & Vectors
影响因子:3.5
doi:10.1186/s13071-025-07076-4
Amieva, Rafael; Rico-San Román, Laura; Pastor-Fernández, Iván; Hemphill, Andrew; Boubaker, Ghalia; Collantes-Fernández, Esther; Ortega-Mora, Luis Miguel; Horcajo, Pilar
发表日期：2025
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Investigating Antiprotozoal Chemotherapies with Novel Proteomic Tools-Chances and Limitations: A Critical Review

利用新型蛋白质组学工具研究抗原生动物化疗——机遇与局限：一项批判性综述

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms25136903
Müller, Joachim; Boubaker, Ghalia; Müller, Norbert; Uldry, Anne-Christine; Braga-Lagache, Sophie; Heller, Manfred; Hemphill, Andrew
发表日期：2024
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TaqMan-quantitative PCR assays applied in Neospora caninum knock-outs generated through CRISPR-Cas9 allow to determine the copy numbers of integrated dihydrofolate reductase-thymidylate synthase drug selectable markers

利用 CRISPR-Cas9 技术在犬新孢子虫基因敲除株中应用 TaqMan 定量 PCR 检测，可以确定整合的二氢叶酸还原酶-胸苷酸合成酶药物选择标记的拷贝数。

期刊:Frontiers in Cellular and Infection Microbiology
影响因子:4.8
doi:10.3389/fcimb.2024.1419209
Rico-San Román, Laura; Hänggeli, Kai Pascal Alexander; Hemphill, Andrew; Horcajo, Pilar; Collantes-Fernández, Esther; Ortega-Mora, Luis Miguel; Boubaker, Ghalia
发表日期：2024
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In vitro and in vivo activities of a trithiolato-diRuthenium complex conjugated with sulfadoxine against the apicomplexan parasite Toxoplasma gondii

三硫醇二钌配合物与磺胺多辛偶联物对弓形虫（Toxoplasma gondii）的体外和体内活性

期刊:International Journal for Parasitology-Drugs and Drug Resistance
影响因子:3.4
doi:10.1016/j.ijpddr.2024.100544
Boubaker, Ghalia; Bernal, Alice; Vigneswaran, Anitha; Imhof, Dennis; de Sousa, Maria Cristina Ferreira; Hänggeli, Kai Pascal Alexander; Haudenschild, Noé; Furrer, Julien; Păunescu, Emilia; Desiatkina, Oksana; Hemphill, Andrew
发表日期：2024
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Comparative Proteomic Analysis of Toxoplasma gondii RH Wild-Type and Four SRS29B (SAG1) Knock-Out Clones Reveals Significant Differences between Individual Strains

对弓形虫RH野生型和四个SRS29B（SAG1）敲除克隆株的比较蛋白质组学分析揭示了不同毒株之间的显著差异

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms241310454
Hänggeli, Kai Pascal Alexander; Hemphill, Andrew; Müller, Norbert; Heller, Manfred; Uldry, Anne-Christine; Braga-Lagache, Sophie; Müller, Joachim; Boubaker, Ghalia
RS2
发表日期：2023
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Synthesis and Antiparasitic Activity of New Trithiolato-Bridged Dinuclear Ruthenium(II)-arene-carbohydrate Conjugates

新型三硫醇桥联双核钌(II)-芳烃-碳水化合物共轭物的合成及抗寄生虫活性

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules28020902
Holzer, Isabelle; Desiatkina, Oksana; Anghel, Nicoleta; Johns, Serena K; Boubaker, Ghalia; Hemphill, Andrew; Furrer, Julien; Păunescu, Emilia
微生物学
发表日期：2023
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In Vitro versus in Mice: Efficacy and Safety of Decoquinate and Quinoline-O-Carbamate Derivatives against Experimental Infection with Neospora caninum Tachyzoites.

体外与小鼠体内：十喹啉和喹啉-O-氨基甲酸酯衍生物对犬新孢子虫速殖子实验感染的疗效和安全性

期刊:Pathogens
影响因子:3.3
doi:10.3390/pathogens12030447
Ramseier Jessica, Imhof Dennis, Hänggeli Kai Pascal Alexander, Anghel Nicoleta, Boubaker Ghalia, Beteck Richard M, Ortega-Mora Luis-Miguel, Haynes Richard K, Hemphill Andrew
炎症/感染
发表日期：2023
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Single and combination treatment of Toxoplasma gondii infections with a bumped kinase inhibitor and artemisone in vitro and with artemiside in experimentally infected mice

体外实验中，使用激酶抑制剂和青蒿素单独或联合治疗弓形虫感染；在实验感染小鼠中，使用青蒿素治疗弓形虫感染。

期刊:Experimental Parasitology
影响因子:1.6
doi:10.1016/j.exppara.2023.108655
Schlange, Carling; Müller, Joachim; Imhof, Dennis; Hänggeli, Kai Pascal Alexander; Boubaker, Ghalia; Ortega-Mora, Luis-Miguel; Wong, Ho Ning; Haynes, Richard K; Van Voorhis, Wesley C; Hemphill, Andrew
炎症/感染
信号转导
发表日期：2023
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