日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dysregulation of Rac or Rho elicits death of motor neurons and activation of these GTPases is altered in the G93A mutant hSOD1 mouse model of amyotrophic lateral sclerosis.

Rac 或 Rho 失调会导致运动神经元死亡,并且在肌萎缩侧索硬化症的 G93A 突变 hSOD1 小鼠模型中,这些 GTP 酶的激活发生了改变

Stankiewicz Trisha R, Pena Claudia, Bouchard Ron J, Linseman Daniel A

C-terminal binding proteins are essential pro-survival factors that undergo caspase-dependent downregulation during neuronal apoptosis

C端结合蛋白是重要的促生存因子,在神经元凋亡过程中会发生caspase依赖性下调。

Stankiewicz, Trisha R; Schroeder, Emily K; Kelsey, Natalie A; Bouchard, Ron J; Linseman, Daniel A

Calpain plays a central role in 1-methyl-4-phenylpyridinium (MPP+)-induced neurotoxicity in cerebellar granule neurons

钙蛋白酶在1-甲基-4-苯基吡啶(MPP+)诱导的小脑颗粒神经元神经毒性中起着核心作用

Harbison, Richard A; Ryan, Kristen R; Wilkins, Heather M; Schroeder, Emily K; Loucks, F Alexandra; Bouchard, Ron J; Linseman, Daniel A

Caspases indirectly regulate cleavage of the mitochondrial fusion GTPase OPA1 in neurons undergoing apoptosis

半胱天冬酶间接调节凋亡神经元中线粒体融合GTP酶OPA1的裂解

Loucks, F Alexandra; Schroeder, Emily K; Zommer, Amelia E; Hilger, Shea; Kelsey, Natalie A; Bouchard, Ron J; Blackstone, Craig; Brewster, Jay L; Linseman, Daniel A

The p75 neurotrophin receptor can induce autophagy and death of cerebellar Purkinje neurons

p75神经营养因子受体可诱导小脑浦肯野神经元自噬和死亡

Florez-McClure, Maria L; Linseman, Daniel A; Chu, Charleen T; Barker, Phil A; Bouchard, Ron J; Le, Shoshona S; Laessig, Tracey A; Heidenreich, Kim A

Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons

胰岛素样生长因子-I阻断小脑颗粒神经元中Bcl-2相互作用的细胞死亡介质(Bim)的诱导和内在死亡信号传导

Linseman, Daniel A; Phelps, Reid A; Bouchard, Ron J; Le, Shoshona S; Laessig, Tracey A; McClure, Maria L; Heidenreich, Kim A