Nasal anti-CD3 monoclonal antibody ameliorates traumatic brain injury, enhances microglial phagocytosis and reduces neuroinflammation via IL-10-dependent T(reg)-microglia crosstalk.
鼻内抗 CD3 单克隆抗体通过 IL-10 依赖性 T(reg)-小胶质细胞串扰改善创伤性脑损伤，增强小胶质细胞吞噬作用并减少神经炎症
期刊:Nature Neuroscience
影响因子:20
doi:10.1038/s41593-025-01877-7
Izzy Saef, Yahya Taha, Albastaki Omar, Abou-El-Hassan Hadi, Aronchik Michael, Cao Tian, De Oliveira Marilia Garcia, Lu Kuan-Jung, Moreira Thais G, da Silva Patrick, Boucher Masen L, Beauchamp Leah C, S LeServe Danielle, Brandao Wesley Nogueira, Carolina Durão Ana, Lanser Toby, Montini Federico, Lee Joon-Hyuk, Bernstock Joshua D, Kaul Megha, Pasquarelli-do-Nascimento Gabriel, Chopra Kusha, Krishnan Rajesh, Mannix Rebekah, Rezende Rafael M, Quintana Francisco J, Butovsky Oleg, Weiner Howard L
