日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Transcriptomic profiling uncovers mis-splicing and gene fusions in amyotrophic lateral sclerosis

转录组分析揭示肌萎缩侧索硬化症中的错误剪接和基因融合

Xu, Huilin; Petrozziello, Tiziana; Boudi, Adel; Shibata, Shota; Huntress, Sommer S; Shahryari, Alireza; Zhao, Xuefang; Kesavan, Maheswaran; Granucci, Eric J; Castillo Torres, Ayleen L; Monsanto, Ranee Zara B; Lemanski, John; Jana, Bimal; De Esch, Celin E F; Cudkowicz, Merit E; Berry, James D; Brand, Harrison; Talkowski, Michael E; Mouro Pinto, Ricardo; Gao, Dadi; Sadri-Vakili, Ghazaleh

Mutant huntingtin exon 1 protein detected in mouse brain with neoepitope antibody: effects of CAG repeat expansion, MutS Homolog 3 silencing and aggregation.

利用新表位抗体在小鼠脑中检测到突变亨廷顿蛋白外显子 1 蛋白:CAG 重复扩增、MutS 同源物 3 沉默和聚集的影响

Sapp Ellen, Boudi Adel, Iwanowicz Andrew, Belgrad Jillian, Miller Rachael, Robertson Riannon, O'Reilly Daniel, Yamada Ken, Deng Yunping, Joni Marion, Li Xueyi, Kegel-Gleason Kimberly, Khvorova Anastasia, Reiner Anton, Aronin Neil, DiFiglia Marian

Mutant Huntingtin exon1 protein detected in mouse brain with neoepitope antibody: effects of CAG repeat expansion, MSH3 silencing, and aggregation

利用新表位抗体在小鼠脑中检测到突变型亨廷顿蛋白外显子1:CAG重复序列扩增、MSH3沉默和聚集的影响

Sapp, Ellen; Boudi, Adel; Iwanowicz, Andrew; Belgrad, Jillian; Miller, Rachael; Robertson, Riannon; O'Reilly, Daniel; Yamada, Ken; Deng, Yunping; Joni, Marion; Li, Xueyi; Kegel-Gleason, Kimberly; Khvorova, Anastasia; Reiner, Anton; Aronin, Neil; DiFiglia, Marian

Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease

二价siRNA介导的MSH3沉默可阻断亨廷顿病小鼠模型中的体细胞重复序列扩增

O'Reilly, Daniel; Belgrad, Jillian; Ferguson, Chantal; Summers, Ashley; Sapp, Ellen; McHugh, Cassandra; Mathews, Ella; Boudi, Adel; Buchwald, Julianna; Ly, Socheata; Moreno, Dimas; Furgal, Raymond; Luu, Eric; Kennedy, Zachary; Hariharan, Vignesh; Monopoli, Kathryn; Yang, X William; Carroll, Jeffery; DiFiglia, Marian; Aronin, Neil; Khvorova, Anastasia