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研究领域:
疾病研究:
种属:
实验技术:
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检测指标:
日期
影响因子
日期:
2020 年 — 2026 年
2020
2021
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2023
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2026
影响因子:
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筛选
Evolutionary analysis reveals the origin of sodium coupling in glutamate transporters
进化分析揭示了谷氨酸转运体中钠偶联的起源
期刊:
Nature Structural & Molecular Biology
影响因子:
10.1
doi:
10.1038/s41594-025-01652-z
Reddy, Krishna D; Rasool, Burha; Akher, Farideh Badichi; Kutlešić, Nemanja; Pant, Swati; Boudker, Olga
Structural basis of excitatory amino acid transporter 3 substrate recognition.
兴奋性氨基酸转运体3底物识别的结构基础
期刊:
Proceedings of the National Academy of Sciences of the United States of America
影响因子:
9.1
doi:
10.1073/pnas.2501627122
Qiu Biao, Boudker Olga
Mechanism and Structure-Guided Optimization of SLC1A1/EAAT3-Selective Inhibitors in Kidney Cancer.
肾癌中 SLC1A1/EAAT3 选择性抑制剂的机制和结构导向优化
期刊:
影响因子:
doi:
10.1101/2025.07.03.663021
Koochaki Pooneh, Qiu Biao, Coker Jesse A, Earsley Alexander, Wang Nancy S, Romigh Todd, Goins Christopher M, Stauffer Shaun R, Boudker Olga, Chakraborty Abhishek A
肿瘤
肾癌
肿瘤免疫
HS-AFM single-molecule structural biology uncovers basis of transporter wanderlust kinetics.
高速原子力显微镜单分子结构生物学揭示了转运蛋白游走动力学的基础
期刊:
Nature Structural & Molecular Biology
影响因子:
10.1
doi:
10.1038/s41594-024-01260-3
Jiang Yining, Miyagi Atsushi, Wang Xiaoyu, Qiu Biao, Boudker Olga, Scheuring Simon
免疫/内分泌
Free fatty acids inhibit an ion-coupled membrane transporter by dissipating the ion gradient.
游离脂肪酸通过耗散离子梯度来抑制离子偶联膜转运蛋白
期刊:
Journal of Biological Chemistry
影响因子:
3.9
doi:
10.1016/j.jbc.2024.107955
Wang Xiaoyu, Rusinova Radda, Gregorio G Glenn, Boudker Olga
免疫/内分泌
The archaeal glutamate transporter homologue GltPh shows heterogeneous substrate binding
古细菌谷氨酸转运蛋白同源物GltPh表现出异质性底物结合能力。
期刊:
Journal of General Physiology
影响因子:
2.9
doi:
10.1085/jgp.202213131
Reddy, Krishna D; Ciftci, Didar; Scopelliti, Amanda J; Boudker, Olga
微生物学
Linking function to global and local dynamics in an elevator-type transporter
将功能与电梯式传送器的全局和局部动力学联系起来
期刊:
Proceedings of the National Academy of Sciences of the United States of America
影响因子:
9.1
doi:
10.1073/pnas.2025520118
Ciftci, Didar; Martens, Chloe; Ghani, Vishnu G; Blanchard, Scott C; Politis, Argyris; Huysmans, Gerard H M; Boudker, Olga
The high-energy transition state of the glutamate transporter homologue GltPh
谷氨酸转运蛋白同源物 GltPh 的高能过渡态
期刊:
EMBO Journal
影响因子:
8.3
doi:
10.15252/embj.2020105415
Huysmans, Gerard H M; Ciftci, Didar; Wang, Xiaoyu; Blanchard, Scott C; Boudker, Olga
Large domain movements through the lipid bilayer mediate substrate release and inhibition of glutamate transporters
脂质双层中大结构域的运动介导底物释放和谷氨酸转运体的抑制
期刊:
Elife
影响因子:
6.4
doi:
10.7554/eLife.58417
Wang, Xiaoyu; Boudker, Olga
A facile approach for the in vitro assembly of multimeric membrane transport proteins
一种简便的体外组装多聚体膜转运蛋白的方法
期刊:
Elife
影响因子:
6.4
doi:
10.7554/eLife.36478
Riederer, Erika A; Focke, Paul J; Georgieva, Elka R; Akyuz, Nurunisa; Matulef, Kimberly; Borbat, Peter P; Freed, Jack H; Blanchard, Scott C; Boudker, Olga; Valiyaveetil, Francis I
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