日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

FGD3 mediates lytic cell death, enhancing efficacy and immunogenicity of chemotherapy agents in breast cancer.

FGD3 介导细胞溶解性死亡,增强化疗药物在乳腺癌中的疗效和免疫原性。

Zhu Junyao, Dai Xinyi, Ghosh Santanu, Wei Elaine, Mao Chengjian, Jiang Qianjin, Spaulding Abigail J, Mulligan Michael P, Romero Roger, Han Yoo Jane, Boudreau Matthew W, Olopade Olufunmilayo, Hergenrother Paul J, Shapiro David J

Single Dose of a Small Molecule Leads to Complete Regressions of Large Breast Tumors in Mice

单次注射小分子药物可使小鼠体内大型乳腺肿瘤完全消退

Mulligan, Michael P; Boudreau, Matthew W; Bouwens, Brooke A; Lee, Yoongyeong; Carrell, Hunter W; Zhu, Junyao; Mousses, Spyro; Shapiro, David J; Nelson, Erik R; Fan, Timothy M; Hergenrother, Paul J

A necrosis inducer promotes an immunogenic response and destroys ovarian cancers in mouse xenografts and patient ascites organoids.

坏死诱导剂可促进免疫反应,并破坏小鼠异种移植和患者腹水类器官中的卵巢癌

Duraki Darjan, Jabeen Musarrat, Mao Chengjian, Wang Lawrence, Ghosh Santanu, Dai Xinyi, Zhu Junyao, Boudreau Matthew W, Nelson Erik R, Hergenrother Paul J, Cheng Georgina, Shapiro David J

Positive Selection Screen for Natural Product β-Catenin Inactivators

天然产物β-catenin失活剂的阳性选择筛选

Boudreau, Matthew W; Freire, Vitor F; Corbett, Sophie C; Martínez-Fructuoso, Lucero; Kumar, Rohitesh; Thornburg, Christopher C; Akee, Rhone K; Peyser, Brian D; Jiang, Qinqin; Splaine, Jennifer; Pfaff, Jamie L; Chandler, Benjamin C; Abeja, Dinah M; Donovan, Katherine A; Che, Jianwei; Lampson, Benjamin L; Szajner, Patricia; Smith, Jennifer A; Koduri, Vidyasagar; Grkovic, Tanja; O'Keefe, Barry R; Kaelin, William G Jr

Isopentyl-Deoxynboquinone Induces Mitochondrial Dysfunction and G2/M Phase Cell Cycle Arrest to Selectively Kill NQO1-Positive Pancreatic Cancer Cells.

异戊基脱氧萘醌诱导线粒体功能障碍和 G2/M 期细胞周期阻滞,从而选择性地杀死 NQO1 阳性胰腺癌细胞

Jiang Lingxiang, Liu Yingchun, Tumbath Soumya, Boudreau Matthew W, Chatkewitz Lindsay E, Wang Jiangwei, Su Xiaolin, Zahid Kashif Rafiq, Li Katherine, Chen Yaomin, Yang Kai, Hergenrother Paul J, Huang Xiumei

YMCC and YSN: An Opportunity for Scientific and Cultural Exchange

YMCC和YSN:科学与文化交流的契机

Ferrins, Lori; Olson, Margaret E; Haranahalli, Krupanandan; Grenier-Davies, Melissa C; Boudreau, Matthew W; Matagne, Brieuc; Donckele, Etienne J; Borsari, Chiara

The combination of PAC-1 and entrectinib for the treatment of metastatic uveal melanoma.

PAC-1 与恩曲替尼联合治疗转移性葡萄膜黑色素瘤

Boudreau Matthew W, Tonogai Emily J, Schane Claire P, Xi Min X, Fischer James H, Vijayakumar Jayanthi, Ji Yan, Tarasow Theodore M, Fan Timothy M, Hergenrother Paul J, Dudek Arkadiusz Z

Evolution of 3-(4-hydroxyphenyl)indoline-2-one as a scaffold for potent and selective anticancer activity

3-(4-羟基苯基)吲哚啉-2-酮作为高效选择性抗癌活性骨架的演变

Boudreau, Matthew W; Hergenrother, Paul J

A small-molecule activator of the unfolded protein response eradicates human breast tumors in mice

一种小分子未折叠蛋白反应激活剂可根除小鼠体内的人类乳腺肿瘤。

Boudreau, Matthew W; Duraki, Darjan; Wang, Lawrence; Mao, Chengjian; Kim, Ji Eun; Henn, Madeline A; Tang, Bingtao; Fanning, Sean W; Kiefer, Jeffrey; Tarasow, Theodore M; Bruckheimer, Elizabeth M; Moreno, Ramon; Mousses, Spyro; Greene, Geoffrey L; Roy, Edward J; Park, Ben Ho; Fan, Timothy M; Nelson, Erik R; Hergenrother, Paul J; Shapiro, David J

Procaspase-3 Overexpression in Cancer: A Paradoxical Observation with Therapeutic Potential

癌症中前体caspase-3的过度表达:一个具有治疗潜力的悖论性现象

Boudreau, Matthew W; Peh, Jessie; Hergenrother, Paul J