日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structural and functional characterization of TgGSK3, a druggable kinase in Toxoplasma gondii

弓形虫中可成药激酶TgGSK3的结构和功能表征

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-64701-7
Diaz-Martin, Silvia; Swale, Christopher; Bellini, Valeria; Dobrescu, Irina; Wenker, Janine; Brenier-Pinchart, Marie-Pierre; Braun, Laurence; Tollec, Alwéna; Corrao, Charlotte; Couté, Yohann; Mas, Caroline; Laurent, Fabrice; Bowler, Matthew; Hakimi, Mohamed-Ali; Bougdour, Alexandre
信号转导
GSK3
发表日期：2025
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Uncovering biomarkers for chronic toxoplasmosis detection highlights alternative pathways shaping parasite dormancy.

发现用于检测慢性弓形虫病的生物标志物，揭示了影响寄生虫休眠的替代途径

期刊:EMBO Molecular Medicine
影响因子:8.3
doi:10.1038/s44321-025-00252-0
Robert Marie G, Swale Christopher, Pachano Belen, Dépéry Léa, Bellini Valeria, Dard Céline, Cannella Dominique, Corrao Charlotte, Belmudes Lucid, Couté Yohann, Bougdour Alexandre, Pelloux Hervé, Chapey Emmanuelle, Wallon Martine, Brenier-Pinchart Marie-Pierre, Hakimi Mohamed-Ali
其它
发表日期：2025
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Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis

通过一系列ATP类似物靶向脯氨酰tRNA合成酶，加速弓形虫病药物的发现

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1011124
Yogavel, Manickam; Bougdour, Alexandre; Mishra, Siddhartha; Malhotra, Nipun; Chhibber-Goel, Jyoti; Bellini, Valeria; Harlos, Karl; Laleu, Benoît; Hakimi, Mohamed-Ali; Sharma, Amit
微生物学
弓形虫病
发表日期：2023
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Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development

双重药物靶向脯氨酰tRNA合成酶为抗感染药物研发提供了一种新的范式。

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1010363
Manickam, Yogavel; Malhotra, Nipun; Mishra, Siddhartha; Babbar, Palak; Dusane, Abhishek; Laleu, Benoît; Bellini, Valeria; Hakimi, Mohamed-Ali; Bougdour, Alexandre; Sharma, Amit
炎症/感染
发表日期：2022
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Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis

以弓形虫CPSF3为靶点控制弓形虫病的新方法

期刊:EMBO Molecular Medicine
影响因子:8.3
doi:10.15252/emmm.201607370
Palencia, Andrés; Bougdour, Alexandre; Brenier-Pinchart, Marie-Pierre; Touquet, Bastien; Bertini, Rose-Laurence; Sensi, Cristina; Gay, Gabrielle; Vollaire, Julien; Josserand, Véronique; Easom, Eric; Freund, Yvonne R; Pelloux, Hervé; Rosenthal, Philip J; Cusack, Stephen; Hakimi, Mohamed-Ali
微生物学
弓形虫病
CPSF3
发表日期：2017
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Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites.

组蛋白 H4 侧面 K31 位点的修饰有助于顶复门寄生虫的基因组结构和表达

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.29391
Sindikubwabo Fabien, Ding Shuai, Hussain Tahir, Ortet Philippe, Barakat Mohamed, Baumgarten Sebastian, Cannella Dominique, Palencia Andrés, Bougdour Alexandre, Belmudes Lucid, Couté Yohann, Tardieux Isabelle, Botté Cyrille Y, Scherf Artur, Hakimi Mohamed-Ali
免疫/内分泌
H4
发表日期：2017
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Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist

内在无序寄生虫分泌的激动剂对MAP激酶信号传导的抑制作用的结构基础

期刊:Structure
影响因子:4.3
doi:10.1016/j.str.2016.10.011
Pellegrini, Erika; Palencia, Andrés; Braun, Laurence; Kapp, Ulrike; Bougdour, Alexandre; Belrhali, Hassan; Bowler, Matthew W; Hakimi, Mohamed-Ali
微生物学
信号转导
发表日期：2017
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The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole

弓形虫致密颗粒蛋白GRA17和GRA23介导宿主和寄生泡之间小分子的运动

期刊:Cell Host & Microbe
影响因子:18.7
doi:10.1016/j.chom.2015.04.003
Gold, Daniel A; Kaplan, Aaron D; Lis, Agnieszka; Bett, Glenna C L; Rosowski, Emily E; Cirelli, Kimberly M; Bougdour, Alexandre; Sidik, Saima M; Beck, Josh R; Lourido, Sebastian; Egea, Pascal F; Bradley, Peter J; Hakimi, Mohamed-Ali; Rasmusson, Randall L; Saeij, Jeroen P J
发表日期：2015
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Anti-adaptors provide multiple modes for regulation of the RssB adaptor protein

反义衔接蛋白为调控RssB衔接蛋白提供了多种模式。

期刊:Genes & Development
影响因子:7.7
doi:10.1101/gad.229617.113
Battesti, Aurelia; Hoskins, Joel R; Tong, Song; Milanesio, Paola; Mann, Jessica M; Kravats, Andrea; Tsegaye, Yodit M; Bougdour, Alexandre; Wickner, Sue; Gottesman, Susan
信号转导
发表日期：2013
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Modulating RssB activity: IraP, a novel regulator of sigma(S) stability in Escherichia coli

调节 RssB 活性：IraP，大肠杆菌中 σ(S) 稳定性的新型调节因子

期刊:Genes & Development
影响因子:7.7
doi:10.1101/gad.1400306
Bougdour, Alexandre; Wickner, Sue; Gottesman, Susan
发表日期：2006
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