日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human Polyclonal Antibodies Produced by Transchromosomal Cattle Provide Partial Protection Against Lethal Zaire Ebolavirus Challenge in Rhesus Macaques

转基因牛产生的人类多克隆抗体可为恒河猴提供针对致命性扎伊尔埃博拉病毒的部分保护

Rosenke, Kyle; Bounds, Callie E; Hanley, Patrick W; Saturday, Greg; Sullivan, Eddie; Wu, Hua; Jiao, Jin-An; Feldmann, Heinz; Schmaljohn, Connie; Safronetz, David

An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transgenic mice.

利用免疫信息学方法制备的DNA疫苗,编码埃博拉病毒、苏丹病毒和委内瑞拉马脑炎病毒的人类II类T细胞表位,在HLA转基因小鼠中具有免疫原性

Bounds Callie E, Terry Frances E, Moise Leonard, Hannaman Drew, Martin William D, De Groot Anne S, Suschak John J, Dupuy Lesley C, Schmaljohn Connie S

Codon-optimized filovirus DNA vaccines delivered by intramuscular electroporation protect cynomolgus macaques from lethal Ebola and Marburg virus challenges.

通过肌肉注射电穿孔技术递送的密码子优化丝状病毒DNA疫苗可保护食蟹猴免受致命的埃博拉病毒和马尔堡病毒的攻击

Grant-Klein Rebecca J, Altamura Louis A, Badger Catherine V, Bounds Callie E, Van Deusen Nicole M, Kwilas Steven A, Vu Hong A, Warfield Kelly L, Hooper Jay W, Hannaman Drew, Dupuy Lesley C, Schmaljohn Connie S

Vaccine generated immunity targets an HPV16 E7 HLA-A2.1-restricted CD8(+) T cell epitope relocated to an early gene or a late gene of the cottontail rabbit papillomavirus (CRPV) genome in HLA-A2.1 transgenic rabbits

疫苗产生的免疫力靶向 HLA-A2.1 转基因兔中棉尾兔乳头瘤病毒 (CRPV) 基因组早期基因或晚期基因上的 HPV16 E7 HLA-A2.1 限制性 CD8(+) T 细胞表位。

Bounds, Callie E; Hu, Jiafen; Cladel, Nancy M; Balogh, Karla; Christensen, Neil D