日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure of the hibernating Francisella tularensis ribosome and mechanistic insights into its inhibition by antibiotics

休眠弗朗西斯菌核糖体的结构及其被抗生素抑制的机制研究

Klima, Martin; Silhan, Jan; Pavlik, Pavla; Hercik, Kamil; Boura, Evzen

Phosphatidylinositol transfer protein α binds microcolins in its open conformation

磷脂酰肌醇转移蛋白α在其开放构象下与微球蛋白结合

Eisenreichova, Andrea; Klima, Martin; Balla, Tamas; Boura, Evzen

Mechanistic insights into alcohol-induced DNA crosslink repair by Slx4-Xpf-Ercc1 nuclease complex in the Fanconi anaemia pathway

范可尼贫血通路中Slx4-Xpf-Ercc1核酸酶复合物介导的酒精诱导DNA交联修复机制研究

Havlikova, Jana; Dejmek, Milan; Huskova, Andrea; Allan, Anthony; Boura, Evzen; Nencka, Radim; Silhan, Jan

Structural Insights into Salinosporamide a Mediated Inhibition of the Human 20S Proteasome.

Salinosporamide 介导的人类 20S 蛋白酶体抑制的结构见解

Sülzen Hagen, Fajtova Pavla, O'Donoghue Anthony J, Silhan Jan, Boura Evzen

Structural basis for broad-spectrum binding of AT-9010 to flaviviral methyltransferases

AT-9010与黄病毒甲基转移酶广谱结合的结构基础

Krejcova, Katerina; Boura, Evzen

Recombinant proteasome provides new avenues for anti-malarial drug development.

重组蛋白酶体为抗疟药物的研发提供了新的途径

Fajtova Pavla, Zhang Hanxiao, Urich Liam, da Silva Elany Barbosa, da Silva Cesar Hoffmann, Almaliti Jehad, Al-Hindy Momen, Boura Evzen, Fidock David A, Kirkman Laura A, Lin Gang, Bogyo Matthew, Gerwick William H, Zhao Jianhua, O'Donoghue Anthony J

Structural insights into Salinosporamide A mediated inhibition of the human 20S proteasome.

盐霉素A介导的人类20S蛋白酶体抑制的结构见解

Sülzen Hagen, Fajtova Pavla, O'Donoghue Anthony J, Boura Evzen, Silhan Jan

Distinct substrate specificities of the three catalytic subunits of the Trichomonas vaginalis proteasome.

阴道毛滴虫蛋白酶体的三个催化亚基具有不同的底物特异性

Fajtova Pavla, Hurysz Brianna M, Miyamoto Yukiko, Serafim Mateus Sá M, Jiang Zhenze, Vazquez Julia M, Trujillo Diego F, Liu Lawrence J, Somani Urvashi, Almaliti Jehad, Myers Samuel A, Caffrey Conor R, Gerwick William H, McMinn Dustin L, Kirk Christopher J, Boura Evzen, Eckmann Lars, O'Donoghue Anthony J

Structure of SARS-CoV-2 MTase nsp14 with the inhibitor STM957 reveals inhibition mechanism that is shared with a poxviral MTase VP39

SARS-CoV-2 甲基转移酶 nsp14 与抑制剂 STM957 的结构揭示了其与痘病毒甲基转移酶 VP39 共有的抑制机制。

Zilecka, Eva; Klima, Martin; Stefek, Milan; Dejmek, Milan; Nencka, Radim; Boura, Evzen

Coordination of transporter, cargo, and membrane properties during non-vesicular lipid transport

非囊泡脂质运输过程中转运蛋白、货物和膜特性之间的协调

Ballekova, Alena; Eisenreichova, Andrea; Różycki, Bartosz; Boura, Evzen; Humpolickova, Jana