日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Validating and Using Cardiac NAMs for Toxicity Screening and Drug Development

验证和利用心脏NAMs进行毒性筛选和药物开发

Pierson, Jennifer Beck; Bahinski, Anthony; Berridge, Brian; Bramham, Daniel; Bourcier, Todd; Chaudhary, Khuram W; Eldridge, Sandy; Kanda, Yasunari; Mattes, William B; Oliphant, Jessica; Pang, Li; Savtchenko, Alex; Siegel, Jeffery; Simpson, Natalie; Tu, Chengyi; Wange, Ronald; Wu, Joseph C; Yang, Xi

ICH S1 prospective evaluation study: weight of evidence approach to predict outcome and value of 2-year rat carcinogenicity studies. A report from the regulatory authorities subgroup

ICH S1 前瞻性评价研究:采用证据权重法预测结果及2年大鼠致癌性研究的价值。监管机构小组报告

Bourcier, Todd; McGovern, Timothy; Cavaliero, Tania; Ebere, Geoffrey; Nishikawa, Akiyoshi; Nishimura, Jihei; Ogawa, Kumiko; Pasanen, Markku; Vespa, Alisa; Van der Laan, Jan Willem

The omega-3 fatty acid docosahexaenoate attenuates endothelial cyclooxygenase-2 induction through both NADP(H) oxidase and PKC epsilon inhibition.

ω-3 脂肪酸二十二碳六烯酸通过抑制 NADP(H) 氧化酶和 PKC ε 来减弱内皮环氧合酶-2 的诱导

Massaro Marika, Habib Aida, Lubrano Laura, Del Turco Serena, Lazzerini Guido, Bourcier Todd, Weksler Babette B, De Caterina Raffaele