日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Caloric restriction delays yeast chronological aging by remodeling carbohydrate and lipid metabolism, altering peroxisomal and mitochondrial functionalities, and postponing the onsets of apoptotic and liponecrotic modes of regulated cell death.

热量限制通过重塑碳水化合物和脂质代谢、改变过氧化物酶体和线粒体功能以及推迟凋亡和脂质坏死等受调控细胞死亡方式的发生,来延缓酵母的自然衰老

Arlia-Ciommo Anthony, Leonov Anna, Beach Adam, Richard Vincent R, Bourque Simon D, Burstein Michelle T, Kyryakov Pavlo, Gomez-Perez Alejandra, Koupaki Olivia, Feldman Rachel, Titorenko Vladimir I

Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes.

化学遗传筛选发现石胆酸是一种抗衰老化合物,它通过调节管家长寿保证过程,以不依赖于 TOR 的方式延长酵母的寿命

Goldberg Alexander A, Richard Vincent R, Kyryakov Pavlo, Bourque Simon D, Beach Adam, Burstein Michelle T, Glebov Anastasia, Koupaki Olivia, Boukh-Viner Tatiana, Gregg Christopher, Juneau Mylène, English Ann M, Thomas David Y, Titorenko Vladimir I

A quantitative assessment of the yeast lipidome using electrospray ionization mass spectrometry

利用电喷雾电离质谱法对酵母脂质组进行定量分析

Bourque, Simon D; Titorenko, Vladimir I