日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synthetic α-synuclein fibrils replicate in mice causing MSA-like pathology.

合成的α-突触核蛋白原纤维在小鼠体内复制,导致类似MSA的病理。

Burger Domenic, Kashyrina Marianna, van den Heuvel Lukas, de La Seiglière Hortense, Lewis Amanda J, De Nuccio Francesco, Mohammed Inayathulla, Verchère Jérémy, Feuillie Cécile, Berbon Mélanie, Arotcarena Marie-Laure, Retailleau Aude, Bezard Erwan, Canron Marie-Hélène, Meissner Wassilios G, Loquet Antoine, Bousset Luc, Poujol Christel, Nilsson K Peter R, Laferrière Florent, Baron Thierry, Lofrumento Dario Domenico, De Giorgi Francesca, Stahlberg Henning, Ichas François

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

RAD50错义变异对DNA损伤反应和有丝分裂进程的影响各不相同。

Redeker, Hanna; Kebel, Swantje; Völkening, Lea; Vatselia, Anna; Weinhold, Louisa; Asgedom, Girmay; Schambach, Axel; Schindler, Detlev; Dörk, Thilo; Bousset, Kristine

Aptamer binding footprints discriminate α-synuclein fibrillar polymorphs from different synucleinopathies

适体结合足迹可区分 α-突触核蛋白纤维多态性与不同的突触核蛋白病

Alix Bouvier-Müller, Deborah Fourmy, Alexis Fenyi, Luc Bousset, Ronald Melki, Frédéric Ducongé

Detection of senescence using machine learning algorithms based on nuclear features

基于核特征的机器学习算法检测衰老

Imanol Duran,Joaquim Pombo,Bin Sun,Suchira Gallage   ,Hiromi Kudo,Domhnall McHugh,Laura Bousset,Jose Efren Barragan Avila,Roberta Forlano,Pinelopi Manousou,Mathias Heikenwalder ,Dominic J Withers,Santiago Vernia,Robert D Goldin,Jesús Gil

A deep intronic mutation causes RAD50 deficiency through an unusual mechanism of distant exon activation

深内含子突变通过一种不寻常的远端外显子激活机制导致 RAD50 缺陷。

Bousset, Kristine; Donega, Stefano; Ameziane, Najim; Fleischhammer, Tabea; Ramachandran, Dhanya; Poley-Gil, Miriam; Schindler, Detlev; van de Laar, Ingrid M; Pagani, Franco; Dörk, Thilo

Magnetic resonance imaging, water relation, gene expression and biochemical data for analysis of the effects of water stress on potato plant functioning and tuber development and quality

利用磁共振成像、水分关系、基因表达和生化数据分析水分胁迫对马铃薯植株功能、块茎发育和品质的影响

Musse, Maja; Challois, Sylvain; Hajjar, Ghina; Quellec, Stéphane; Radovcic, Aël; Ali, Nusrat; Berardocco, Solenne; Dumont, Doriane; Laugier, Patricia; Leconte, Patrick; Carrillo, Aurélien; Langrume, Christophe; Bousset-Vaslin, Lydia; Billiot, Bastien; Jamois, Franck; Deleu, Carole; Leport, Laurent

Long term worsening of amyloid pathology, cerebral function, and cognition after a single inoculation of beta-amyloid seeds with Osaka mutation

单次接种大阪突变的 β-淀粉样蛋白种子后,淀粉样蛋白病理、脑功能和认知能力会出现长期恶化

Marina Célestine, Muriel Jacquier-Sarlin, Eve Borel, Fanny Petit, Jean-Baptiste Perot, Anne-Sophie Hérard, Luc Bousset, Alain Buisson, Marc Dhenain

Synapses do not facilitate prion-like transfer of alpha-synuclein: a quantitative study in reconstructed unidirectional neural networks.

突触不会促进 α-突触核蛋白的朊病毒样转移:一项在重建的单向神经网络中进行的定量研究

Courte Josquin, Le Ngoc Anh, Pan Teng, Bousset Luc, Melki Ronald, Villard Catherine, Peyrin Jean-Michel

A phase IV study evaluating QT interval, pharmacokinetics, and safety following fractionated dosing of gemtuzumab ozogamicin in patients with relapsed/refractory CD33-positive acute myeloid leukemia

一项 IV 期研究评估了吉妥珠单抗奥佐米星分次给药治疗复发/难治性 CD33 阳性急性髓系白血病患者的 QT 间期、药代动力学和安全性。

Montesinos, Pau; Kota, Vamsi; Brandwein, Joseph; Bousset, Pierre; Benner, Rebecca J; Vandendries, Erik; Chen, Ying; McMullin, Mary Frances

Propagation of Distinct α-Synuclein Strains Within Human Reconstructed Neuronal Network and Associated Neuronal Dysfunctions

不同 α-突触核蛋白菌株在人类重建神经元网络中的传播及相关神经元功能障碍

Simona Gribaudo, Luc Bousset, Josquin Courte, Ronald Melki, Jean-Michel Peyrin, Anselme L Perrier