日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Age-related macular degeneration and cerebral amyloid angiopathy have similar pathologies from cholesterol-APOE-amyloid-β-complement mediated inflammation

年龄相关性黄斑变性和脑淀粉样血管病具有相似的病理机制,均源于胆固醇-APOE-β淀粉样蛋白-补体介导的炎症反应。

Stuard Sambhariya, Whitney; Bowes Rickman, Catherine; D'Amore, Patricia A; Corradetti, Giulia; Hageman, Gregory S; Howell, Gareth R; Marola, Olivia J; Phatnani, Hemali; Philp, Nancy J; Sinha, Debasish; Toomey, Christopher B; Stone, Faith; Eberhart, Charles; Handa, James T

Truncated complement factor H Y402 gene therapy rescues C3 glomerulonephritis

截短补体因子H Y402基因疗法可挽救C3肾小球肾炎

Chew, Lindsey A; Grigsby, Daniel; Hester, C Garren; Amason, Joshua; McPherson, W Kyle; Flynn, Edward J 3rd; Visel, Meike; Starr, Christopher R; Flannery, John G; Lewis, Tylor R; Bowes Rickman, Catherine

Dissecting the biological complexity of age-related macular degeneration: Is it one disease, multiple separate diseases, or a spectrum?

剖析年龄相关性黄斑变性的生物学复杂性:它是一种疾病、多种独立的疾病,还是一个疾病谱?

Miller, Jason M L; Thompson, Benjamin R; Handa, James T; Luthert, Philip; Chakravarthy, Usha; Csaky, Karl G; Bird, Alan; Young, Benjamin K; Iyengar, Sudha K; Baek, Jiwon; Zouache, Moussa A; Richards, Burt T; Hageman, Gregory S; Rodrigues, Gerry; Bharti, Kapil; Flannery, John G; Gorin, Michael B; Bowes Rickman, Catherine

Optimized Minimally Invasive Transscleral Subretinal Injection Technique in Mouse

小鼠优化微创经巩膜视网膜下注射技术

Cao, Lauren Y; Chew, Lindsey A; Finkelstein, Stella; Amason, Josh; Dubey, Sushil K; Flynn, Edward; Arshavsky, Vadim Y; Bowes Rickman, Catherine; Alekseev, Oleg

A Protocol to Evaluate and Quantify Retinal Pigmented Epithelium Pathologies in Mouse Models of Age-Related Macular Degeneration

评估和量化小鼠年龄相关性黄斑变性模型中视网膜色素上皮病变的方案

Landowski, Michael; Grindel, Samuel; Hao, Ying; Ikeda, Sakae; Bowes Rickman, Catherine; Ikeda, Akihiro

Cell culture models to study retinal pigment epithelium-related pathogenesis in age-related macular degeneration

利用细胞培养模型研究年龄相关性黄斑变性中视网膜色素上皮相关的发病机制

Bharti, Kapil; den Hollander, Anneke I; Lakkaraju, Aparna; Sinha, Debasish; Williams, David S; Finnemann, Silvia C; Bowes-Rickman, Catherine; Malek, Goldis; D'Amore, Patricia A

Targeting Lipid Metabolism for the Treatment of Age-Related Macular Degeneration: Insights from Preclinical Mouse Models

靶向脂质代谢治疗年龄相关性黄斑变性:来自临床前小鼠模型的启示

Landowski, Michael; Bowes Rickman, Catherine

Microglial Function Is Distinct in Different Anatomical Locations during Retinal Homeostasis and Degeneration

在视网膜稳态和退化过程中,小胶质细胞在不同解剖位置的功能各不相同。

O'Koren, Emily G; Yu, Chen; Klingeborn, Mikael; Wong, Alicia Y W; Prigge, Cameron L; Mathew, Rose; Kalnitsky, Joan; Msallam, Rasha A; Silvin, Aymeric; Kay, Jeremy N; Bowes Rickman, Catherine; Arshavsky, Vadim Y; Ginhoux, Florent; Merad, Miriam; Saban, Daniel R

Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice.

人类补体因子 H Y402H 多态性导致小鼠出现与年龄相关的黄斑变性表型和脂蛋白失调

Landowski Michael, Kelly Una, Klingeborn Mikael, Groelle Marybeth, Ding Jin-Dong, Grigsby Daniel, Bowes Rickman Catherine

Complement factor H in AMD: Bridging genetic associations and pathobiology

补体因子H在年龄相关性黄斑变性中的作用:连接遗传关联与病理生物学

Toomey, Christopher B; Johnson, Lincoln V; Bowes Rickman, Catherine