日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

trans-Translation inhibitors that kill M. tuberculosis and pathogenic Non-tuberculous Mycobacteria have a dual mechanism of action

能杀死结核分枝杆菌和致病性非结核分枝杆菌的翻译抑制剂具有双重作用机制。

Varshney, Akanksha; Jia, Ziyi; Gebretsadik, Gebremichal; G-Dayanandan, Narendran; Bowlin, Terry L; Butler, Michelle M; Baughn, Anthony D; Keiler, Kenneth C

N-arylpyrimidinamine (NAPA) compounds are broadly acting inhibitors of human cytomegalovirus infection and spread

N-芳基嘧啶胺(NAPA)化合物是广谱的人类巨细胞病毒感染和传播抑制剂。

Atanasoff, Kristina E; Ophir, Sabrina I; Parsons, Andrea J; Paredes Casado, Jailene; Lurain, Nell S; Bowlin, Terry L; Opperman, Timothy J; Tortorella, Domenico

Identification and Characterization of a Metal Binding-Independent Rift Valley Fever Virus Endonuclease Inhibitor

鉴定和表征一种不依赖金属结合的裂谷热病毒核酸内切酶抑制剂

Kirby, Cara D; Liu, Gai; Fatma, Farheen; Pedlow, Maris R; G-Dayanandan, Narendran; Sharma, Nitin; Frey, Zachary D; Rush, Rachael E; Cardinale, Steven C; Krezel, Andrzej M; Hartman, Amy L; Bowlin, Terry L; Leung, Daisy W; Amarasinghe, Gaya K

Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis

Spectinamide MBX-4888A 在晚期小鼠结核病模型中表现出良好的病灶和组织分布,并能缩短治疗时间。

Bauman, Allison A; Sarathy, Jansy P; Kaya, Firat; Massoudi, Lisa M; Scherman, Michael S; Hastings, Courtney; Liu, Jiuyu; Xie, Min; Brooks, Elizabeth J; Ramey, Michelle E; Jones, Isabelle L; Benedict, Noalani D; Maclaughlin, Madelyn R; Miller-Dawson, Jake A; Waidyarachchi, Samanthi L; Butler, Michelle M; Bowlin, Terry L; Zimmerman, Matthew D; Lenaerts, Anne J; Meibohm, Bernd; Gonzalez-Juarrero, Mercedes; Lyons, Michael A; Dartois, Veronique; Lee, Richard E; Robertson, Gregory T

Filociclovir Is a Potent In Vitro and In Vivo Inhibitor of Human Adenoviruses

菲洛西洛韦是一种强效的体外和体内人类腺病毒抑制剂

Toth, Karoly; Hussein, Islam T M; Tollefson, Ann E; Ying, Baoling; Spencer, Jacqueline F; Eagar, Jessica; James, Scott H; Prichard, Mark N; Wold, William S M; Bowlin, Terry L

A Structure-Function-Inhibition Analysis of the Pseudomonas aeruginosa Type III Secretion Needle Protein PscF

铜绿假单胞菌 III 型分泌针状蛋白 PscF 的结构-功能-抑制分析

Moir, Donald T; Bowlin, Nicholas O; Berube, Bryan J; Yabut, Jaden; Mills, Debra M; Nguyen, Giang T; Aron, Zachary D; Williams, John D; Mecsas, Joan; Hauser, Alan R; Bowlin, Terry L

Efficacy of Aminomethyl Spectinomycins against Complex Upper Respiratory Tract Bacterial Infections

氨甲基壮观霉素治疗复杂性上呼吸道细菌感染的疗效

Iverson, Amy; Meyer, Christopher J; Vogel, Peter; Waidyarachchi, Samanthi; Das, Nisha; Bruhn, David F; Poole, Aaron; Butler, Michelle M; Bowlin, Terry L; Lee, Richard E; Rosch, Jason W

Phase Ib Trial To Evaluate the Safety and Pharmacokinetics of Multiple Ascending Doses of Filociclovir (MBX-400, Cyclopropavir) in Healthy Volunteers

一项评估菲洛西洛韦(MBX-400,环丙韦)多次递增剂量在健康志愿者中安全性和药代动力学的 Ib 期试验

Rouphael, Nadine G; Hurwitz, Selwyn J; Hart, Mari; Beck, Allison; Anderson, Evan J; Deye, Gregory; Osborn, Blaire; Cai, Shu Yi; Focht, Chris; Amegashie, Cyrille; Bowlin, Terry L; Brooks, Jennifer; Mulligan, Mark J

Activation of 6-Alkoxy-Substituted Methylenecyclopropane Nucleoside Analogs Requires Enzymatic Modification by Adenosine Deaminase-Like Protein 1

6-烷氧基取代的亚甲基环丙烷核苷类似物的活化需要腺苷脱氨酶样蛋白1的酶促修饰

Vollmer, Kathryn J; Burns, Anna C; Sauer, Hannah E; Williams, John D; Komazin-Meredith, Gloria; Cardinale, Steve; Butler, Michelle; Aron, Zachary; Hussein, Islam; Busch, Marc G; Bowlin, Terry L; Gentry, Brian G

Aminomethyl Spectinomycins as Therapeutics for Drug-Resistant Gonorrhea and Chlamydia Coinfections.

氨甲基壮观霉素作为治疗耐药性淋病和衣原体合并感染的药物

Butler Michelle M, Waidyarachchi Samanthi L, Connolly Kristie L, Jerse Ann E, Chai Weirui, Lee Richard E, Kohlhoff Stephan A, Shinabarger Dean L, Bowlin Terry L