日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inflammatory disease microbiomes share a functional pathogenicity predicted by C-reactive protein

炎症性疾病微生物群具有由C反应蛋白预测的功能性致病性。

Britton, Graham J; Mogno, Ilaria; Chen-Liaw, Alice; Plitt, Tamar; Helmus, Drew; Bongers, Gerold; Brough, India; Colmenero, Paula; Lam, Lilian H; Bullers, Samuel J; Penkava, Frank; Reyes-Mercedes, Pamela; Braun, Jonathan; Jacobs, Jonathan P; Desch, A Nicole; Gevers, Dirk; Simmons, Sheri; Filer, Andrew; Taylor, Peter C; Bowness, Paul; Huttenhower, Curtis; Littman, Dan; Dubinsky, Marla C; Raza, Karim; Tankou, Stephanie K; Faith, Jeremiah J

Pathogenic T-cell clones in axial spondyloarthritis: what is the evidence?

中轴型脊柱关节炎中的致病性 T 细胞克隆:证据是什么?

Penkava, Frank; Sansom, Stephen; Bowness, Paul

Chimeric antigens displaying GPR65 extracellular loops on a soluble scaffold enabled the discovery of antibodies, which recognized native receptor

在可溶性支架上展示 GPR65 胞外环的嵌合抗原,使得人们能够发现识别天然受体的抗体。

Barrett, Janine; Leysen, Seppe; Galmiche, Cécile; Al-Mossawi, Hussein; Bowness, Paul; Edwards, Thomas E; Lawson, Alastair D G

Optimising psoriatic arthritis therapy with immunological methods to increase standard evaluation: the protocol of an open-label multicentre, parallel-group, two-arm randomised controlled study evaluation precision medicine approach in the treatment of psoriatic arthritis

利用免疫学方法优化银屑病关节炎治疗以提高标准评估:一项开放标签、多中心、平行组、双臂随机对照研究方案,旨在评估精准医学方法在银屑病关节炎治疗中的应用

Ooms, Alexander; Al-Mossawi, Hussein; Bennett, Louise; Bogale, Mimi; Bowness, Paul; Francis, Anne; Goodyear, Carl; Kirkham, Bruce W; Lalnunhlimi, Sylvine; McInnes, Iain B; Richards, Duncan; Siebert, Stefan; Taams, Leonie S; Tulunay Virlan, Aysin; Yager, Nicole; Coates, Laura C

Single cell analysis of spondyloarthritis regulatory T cells identifies distinct synovial gene expression patterns and clonal fates

对强直性脊柱炎调节性T细胞的单细胞分析揭示了独特的滑膜基因表达模式和克隆命运

Simone, Davide; Penkava, Frank; Ridley, Anna; Sansom, Stephen; Al-Mossawi, M Hussein; Bowness, Paul

Identification of an Unconventional Subpeptidome Bound to the Behçet's Disease-associated HLA-B*51:01 that is Regulated by Endoplasmic Reticulum Aminopeptidase 1 (ERAP1)

鉴定出一种与白塞氏病相关 HLA-B*51:01 结合的非常规亚肽组,该亚肽组受内质网氨肽酶 1 (ERAP1) 调控

Chen, Liye; Shi, Hui; Koftori, Danai; Sekine, Takuya; Nicastri, Annalisa; Ternette, Nicola; Bowness, Paul

New developments in our understanding of ankylosing spondylitis pathogenesis

我们对强直性脊柱炎发病机制的认识有了新的进展

Voruganti, Aniruddha; Bowness, Paul

A genetics-led approach defines the drug target landscape of 30 immune-related traits

以遗传学为主导的方法确定了30种免疫相关性状的药物靶点图谱。

Fang, Hai; De Wolf, Hans; Knezevic, Bogdan; Burnham, Katie L; Osgood, Julie; Sanniti, Anna; Lledó Lara, Alicia; Kasela, Silva; De Cesco, Stephane; Wegner, Jörg K; Handunnetthi, Lahiru; McCann, Fiona E; Chen, Liye; Sekine, Takuya; Brennan, Paul E; Marsden, Brian D; Damerell, David; O'Callaghan, Chris A; Bountra, Chas; Bowness, Paul; Sundström, Yvonne; Milani, Lili; Berg, Louise; Göhlmann, Hinrich W; Peeters, Pieter J; Fairfax, Benjamin P; Sundström, Michael; Knight, Julian C

Salmonella exploits HLA-B27 and host unfolded protein responses to promote intracellular replication

沙门氏菌利用HLA-B27和宿主未折叠蛋白反应来促进其胞内复制。

Antoniou, Antony Nicodemus; Lenart, Izabela; Kriston-Vizi, Janos; Iwawaki, Takao; Turmaine, Mark; McHugh, Kirsty; Ali, Sadfer; Blake, Neil; Bowness, Paul; Bajaj-Elliott, Mona; Gould, Keith; Nesbeth, Darren; Powis, Simon J

Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation

强直性脊柱炎的等位基因关联与人类白细胞抗原B27同源二聚体的形成无关

Lim Kam Sian, Terry C C; Indumathy, Saranjah; Halim, Hanim; Greule, Anja; Cryle, Max J; Bowness, Paul; Rossjohn, Jamie; Gras, Stephanie; Purcell, Anthony W; Schittenhelm, Ralf B