文献库，生知库 | 链接生命科学的每一步

日期影响因子

FAK inhibition in ovarian cancer releases omega-3 fatty acids to program CXCL13-producing anti-tumor resident peritoneal macrophages.

卵巢癌中 FAK 抑制可释放 omega-3 脂肪酸，从而激活产生 CXCL13 的抗肿瘤驻留腹膜巨噬细胞。

期刊:Cell Reports

影响因子:6.9

doi:10.1016/j.celrep.2026.117009

Chen Xiao Lei, Tharp Kevin M, Ojalill Marjaana, Ozmadenci Duygu, Boyer Antonia, Haanen Terrance J 3rd, Lawson Christine, Lee Hyojae J, Xia Marvin, Tahon Elise, Zhang Yichi, Minor Cray, Khan Safir Ullah, Anderson Colin C, Nemkov Travis, Rose Michael, Estrada Monica V, Molinolo Alfredo A, Warren Elias, Penalosa Patrick, Eskander Ramez N, McHale Michael T, Wang Shizhen E, Connolly Denise C, Fisch Kathleen M, Stupack Dwayne G, Schlaepfer David D

细胞生物学

发表日期：2026

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Liposomal Doxorubicin, but Not Platinum-Taxane, Supports MHC-II Expression and Immune Maturation in the Ovarian Tumor Microenvironment.

脂质体阿霉素（而非铂类-紫杉烷类药物）支持卵巢肿瘤微环境中的 MHC-II 表达和免疫成熟。

影响因子:4.4

doi:10.3390/cancers17172827

Lee Hyojae, Chen Xiao-Lei, Ozmadenci Duygu, Tahon Elise, Haanan Terrance J 3rd, Hill Breana, Khan Safir Ullah, Boyer Antonia, Schlaepfer David D, Stupack Dwayne

免疫/内分泌

肿瘤微环境

发表日期：2025

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Inducible FAK loss but not FAK inhibition in endothelial cells of PYK2-null mice activates p53 tumor suppressor to prevent tumor growth.

PYK2 基因敲除小鼠内皮细胞中 FAK 的诱导性缺失（而非 FAK 的抑制）可激活 p53 肿瘤抑制因子，从而阻止肿瘤生长

期刊:Molecular Biology of the Cell

影响因子:2.7

doi:10.1091/mbc.E24-12-0562

Chen Xiao Lei, Ojalill Marjaana, Jean Christine, Tancioni Isabelle, Jiang Shulin, Boyer Antonia, Ozmadenci Duygu, Uryu Sean, Tarin David, Schlessinger Joseph, Stupack Dwayne G, Schlaepfer David D

细胞生物学

发表日期：2025

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Ovarian Tumor FAK Inhibition Releases Omega-3 Fatty Acids Stimulating GATA6 Peritoneal Macrophage CXCL13 Production Enhancing Immunotherapy.

卵巢肿瘤 FAK 抑制释放 Omega-3 脂肪酸刺激 GATA6 腹膜巨噬细胞 CXCL13 产生，增强免疫疗法。

doi:10.1101/2025.09.12.675975

Chen Xiao Lei, Tharp Kevin M, Ojalill Marjaana, Ozmadenci Duygu, Boyer Antonia, Hannen Iii Terrance J, Lawson Christine, Lee Hyojae James, Xia Marvin, Tahon Elise, Zhang Yichi, Minor Cray, Khan Safir Ullah, Anderson Colin C, Nemkov Travis, Rose Michael, Estrada Monica V, Molinolo Alfredo A, Warren Elias, Penolosa Patrick, Eskander Ramez N, McHale Michael T, Wang Shizhen E, Connolly Denise C, Fisch Kathleen M, Stupack Dwayne G, Schlaepfer David D

细胞生物学

免疫/内分泌

发表日期：2025

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Inducible FAK Deletion but not FAK Inhibition in Endothelial Cells Activates p53 to Suppress Tumor Growth in PYK2-null Mice

内皮细胞中FAK的诱导性缺失而非FAK的抑制可激活p53，从而抑制PYK2基因敲除小鼠的肿瘤生长

doi:10.1101/2024.11.04.622008

Chen, Xiao Lei; Ojalill, Marjaana; Jean, Christine; Tancioni, Isabelle; Jiang, Shulin; Boyer, Antonia; Ozmadenci, Duygu; Uryu, Sean; Tarin, David; Schlessinger, Joseph; Stupack, Dwayne G; Schlaepfer, David D

细胞生物学

发表日期：2024

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Publisher Correction: PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3

出版商更正：PTEN 通过 DAXX 和组蛋白 H3.3 的染色质相关复合物调控胶质母细胞瘤的发生。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/ncomms16217

Benitez, Jorge A; Ma, Jianhui; D'Antonio, Matteo; Boyer, Antonia; Camargo, Maria Fernanda; Zanca, Ciro; Kelly, Stephen; Khodadadi-Jamayran, Alireza; Jameson, Nathan M; Andersen, Michael; Miletic, Hrvoje; Saberi, Shahram; Frazer, Kelly A; Cavenee, Webster K; Furnari, Frank B

细胞生物学

发表日期：2018

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