日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo

表面聚乙二醇(PEG)密度对体外粘液中生物可降解纳米颗粒运输和体内分布的影响

Xu, Qingguo; Ensign, Laura M; Boylan, Nicholas J; Schön, Arne; Gong, Xiaoqun; Yang, Jeh-Chang; Lamb, Nicholas W; Cai, Shutian; Yu, Tao; Freire, Ernesto; Hanes, Justin

Highly compacted pH-responsive DNA nanoparticles mediate transgene silencing in experimental glioma

高度压缩的pH响应性DNA纳米颗粒介导实验性胶质瘤中的转基因沉默

Kim, Anthony J; Woodworth, Graeme F; Boylan, Nicholas J; Suk, Jung Soo; Hanes, Justin

Use of single-site-functionalized PEG dendrons to prepare gene vectors that penetrate human mucus barriers

利用单一位点功能化的PEG树枝状聚合物制备能够穿透人体粘液屏障的基因载体

Kim, Anthony J; Boylan, Nicholas J; Suk, Jung Soo; Hwangbo, Minyoung; Yu, Tao; Schuster, Benjamin S; Cebotaru, Liudimila; Lesniak, Wojciech G; Oh, Joon Seok; Adstamongkonkul, Pichet; Choi, Ashley Y; Kannan, Rangaramanujam M; Hanes, Justin

Scalable method to produce biodegradable nanoparticles that rapidly penetrate human mucus

一种可扩展的方法,用于生产能够快速渗透人体粘液的可生物降解纳米颗粒

Xu, Qingguo; Boylan, Nicholas J; Cai, Shutian; Miao, Bolong; Patel, Himatkumar; Hanes, Justin

Conjugation site heterogeneity causes variable electrostatic properties in Fc conjugates

偶联位点异质性导致Fc偶联物具有不同的静电性质。

Boylan, Nicholas J; Zhou, Wen; Proos, Robert J; Tolbert, Thomas J; Wolfe, Janet L; Laurence, Jennifer S

Enhancement of airway gene transfer by DNA nanoparticles using a pH-responsive block copolymer of polyethylene glycol and poly-L-lysine.

利用聚乙二醇和聚赖氨酸的 pH 响应嵌段共聚物增强 DNA 纳米颗粒对气道基因转移的促进作用

Boylan Nicholas J, Kim Anthony J, Suk Jung Soo, Adstamongkonkul Pichet, Simons Brian W, Lai Samuel K, Cooper Mark J, Hanes Justin

N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles

N-乙酰半胱氨酸通过高度压缩的DNA纳米颗粒增强囊性纤维化痰液的渗透性和气道基因转移

Suk, Jung Soo; Boylan, Nicholas J; Trehan, Kanika; Tang, Benjamin C; Schneider, Craig S; Lin, Jung-Ming G; Boyle, Michael P; Zeitlin, Pamela L; Lai, Samuel K; Cooper, Mark J; Hanes, Justin

Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with N-acetyl cysteine

N-乙酰半胱氨酸处理囊性纤维化痰液后,粘液惰性纳米颗粒的快速转运

Suk, Jung Soo; Lai, Samuel K; Boylan, Nicholas J; Dawson, Michelle R; Boyle, Michael P; Hanes, Justin