日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reduction of sphingomyelinase activity associated with progranulin deficiency and frontotemporal dementia.

鞘磷脂酶活性降低与前粒蛋白缺乏和额颞叶痴呆有关

Boyle Nicholas R, Fox Stephanie N, Tadepalli Aniketh S, Seyfried Nicholas T, Kukar Thomas, Ramos Eliana M, Nana Alissa L, Spina Salvatore, Grinberg Lea T, Miller Bruce L, Seeley William W, Arrant Andrew E, Roberson Erik D

TFEB overexpression alleviates autophagy-lysosomal deficits caused by progranulin insufficiency.

TFEB 过表达可缓解由前粒蛋白不足引起的自噬溶酶体缺陷

Nader Wren O, Brown Kaylan S, Boyle Nicholas R, Kaplelach Azariah K, Abdelaziz Shaimaa M, Davis Skylar E, Aljabi Qays, Hakim Ahmad R, Davidson Amelia G, Vollmer Giacynta A, Wright Leah C, Echols J Bailey, Saad Joelle, Pena Nicholas S, Arrant Andrew E

Preclinical Interventions in Mouse Models of Frontotemporal Dementia Due to Progranulin Mutations

前粒蛋白突变引起的额颞叶痴呆小鼠模型的临床前干预

Kashyap, Shreya N; Boyle, Nicholas R; Roberson, Erik D