Boyle William J相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Preclinical development of ozuriftamab vedotin (BA3021), a novel ROR2-specific conditionally active biologic antibody-drug conjugate.

ozuriftamab vedotin (BA3021) 是一种新型 ROR2 特异性条件活性生物抗体药物偶联物，其临床前开发

影响因子:7.3

doi:10.1080/19420862.2025.2490078

Chang Hwai Wen, Frey Gerhard, Wang Jing, Liu Haizhen, Xing Charles, Chen Jian, Boyle William J, Short Jay M

发表日期：2025

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Preclinical development of mecbotamab vedotin (BA3011), a novel, AXL-specific conditional active biologic antibody-drug conjugate.

mecbotamab vedotin (BA3011) 是一种新型的 AXL 特异性条件活性生物抗体药物偶联物，其临床前开发

期刊:Antibody Therapeutics

影响因子:4.5

doi:10.1093/abt/tbaf006

Chang Hwai Wen, Wang Jing, Liu Haizhen, Xing Charles, Chen Jian, Frey Gerhard, Boyle William J, Short Jay M

发表日期：2025

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A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy

一种新型条件性活性生物制剂抗EpCAM x 抗CD3双特异性抗体，具有协同肿瘤选择性，可用于癌症免疫治疗。

影响因子:7.3

doi:10.1080/19420862.2024.2322562

Frey, Gerhard; Cugnetti, Ana Paula G; Liu, Haizhen; Xing, Charles; Wheeler, Christina; Chang, Hwai Wen; Boyle, William J; Short, Jay M

免疫/内分泌

发表日期：2024

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Generating tumor-selective conditionally active biologic anti-CTLA4 antibodies via protein-associated chemical switches

通过蛋白质相关化学开关生成肿瘤选择性条件活性生物制剂抗CTLA4抗体

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2020606118

Chang, Hwai Wen; Frey, Gerhard; Liu, Haizhen; Xing, Charles; Steinman, Lawrence; Boyle, William J; Short, Jay M

发表日期：2021

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The Use of Somatic Hypermutation for the Affinity Maturation of Therapeutic Antibodies

利用体细胞高频突变进行治疗性抗体的亲和力成熟

期刊:Methods in Molecular Biology

doi:10.1007/978-1-4939-8648-4_24

Bowers, Peter M; Boyle, William J; Damoiseaux, Robert

细胞生物学

发表日期：2018

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Role of RANK ligand in mediating increased bone resorption in early postmenopausal women

RANK配体在介导早期绝经后妇女骨吸收增加中的作用

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI17215

Eghbali-Fatourechi, Guitty; Khosla, Sundeep; Sanyal, Arunik; Boyle, William J; Lacey, David L; Riggs, B Lawrence

发表日期：2003

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