Transgenic parasites stably expressing full-length Plasmodium falciparum circumsporozoite protein as a model for vaccine down-selection in mice using sterile protection as an endpoint
以稳定表达全长恶性疟原虫环子孢子蛋白的转基因寄生虫为模型,在小鼠体内进行疫苗筛选,以无菌保护为终点。
期刊:Clinical and Vaccine Immunology
影响因子:
doi:10.1128/CVI.00066-13
Porter, Michael D; Nicki, Jennifer; Pool, Christopher D; DeBot, Margot; Illam, Ratish M; Brando, Clara; Bozick, Brooke; De La Vega, Patricia; Angra, Divya; Spaccapelo, Roberta; Crisanti, Andrea; Murphy, Jittawadee R; Bennett, Jason W; Schwenk, Robert J; Ockenhouse, Christian F; Dutta, Sheetij