Cell surface CD55 traffics to the nucleus leading to cisplatin resistance and stemness by inducing PRC2 and H3K27 trimethylation on chromatin in ovarian cancer
细胞表面CD55转运至细胞核,通过诱导卵巢癌细胞染色质上的PRC2和H3K27三甲基化,导致顺铂耐药性和干性。
期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-024-02028-5
Bharti, Rashmi; Dey, Goutam; Khan, Debjit; Myers, Alex; Huffman, Olivia G; Saygin, Caner; Braley, Chad; Richards, Elliott; Sangwan, Naseer; Willard, Belinda; Lathia, Justin D; Fox, Paul L; Lin, Feng; Jha, Babal Kant; Brown, J Mark; Yu, Jennifer S; Dwidar, Mohammed; Joehlin-Price, Amy; Vargas, Roberto; Michener, Chad M; Longworth, Michelle S; Reizes, Ofer
肿瘤
表观遗传
CD5
肿瘤免疫
卵巢癌
CD55
细胞生物学