Oncogenic IDH1(mut) drives robust loss of histone acetylation and increases chromatin heterogeneity
致癌的IDH1(突变)导致组蛋白乙酰化水平显著降低,并增加染色质异质性。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2403862122
Furth, Noa; Cohen, Niv; Spitzer, Avishay; Salame, Tomer-Meir; Dassa, Bareket; Mehlman, Tevie; Brandis, Alexander; Moussaieff, Arieh; Friedmann-Morvinski, Dinorah; Castro, Maria G; Fortin, Jerome; Suvà, Mario L; Tirosh, Itay; Erez, Ayelet; Ron, Guy; Shema, Efrat