Anticancer peptide PNC-27 adopts an HDM-2-binding conformation and kills cancer cells by binding to HDM-2 in their membranes
抗癌肽PNC-27采用HDM-2结合构象,通过与癌细胞膜上的HDM-2结合来杀死癌细胞。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.0909364107
Sarafraz-Yazdi, Ehsan; Bowne, Wilbur B; Adler, Victor; Sookraj, Kelley A; Wu, Vernon; Shteyler, Vadim; Patel, Hunaiz; Oxbury, William; Brandt-Rauf, Paul; Zenilman, Michael E; Michl, Josef; Pincus, Matthew R