Decreases in plasma TNF-alpha level and IFN-gamma mRNA level in peripheral blood mononuclear cells (PBMC) and an increase in IL-2 mRNA level in PBMC are associated with effective highly active antiretroviral therapy in HIV-infected patients.
HIV感染患者接受高效抗逆转录病毒治疗后,血浆TNF-α水平和外周血单核细胞(PBMC)中IFN-γ mRNA水平降低,而PBMC中IL-2 mRNA水平升高
期刊:Clinical and Experimental Immunology
影响因子:3.8
doi:10.1046/j.1365-2249.2003.02064.x
Brazille P, Dereuddre-Bosquet N, Leport C, Clayette P, Boyer O, Vildé J-L, Dormont D, Benveniste O