Combinations of an acetyl CoA carboxylase inhibitor with hepatic lipid modulating agents do not augment antifibrotic efficacy in preclinical models of NASH and fibrosis
在非酒精性脂肪性肝炎和纤维化的临床前模型中,乙酰辅酶A羧化酶抑制剂与肝脏脂质调节剂联合使用并不能增强抗纤维化疗效。
期刊:Hepatology Communications
影响因子:4.6
doi:10.1002/hep4.2011
Vijayakumar, Archana; Okesli-Armlovich, Ayse; Wang, Ting; Olson, Isabel; Seung, Minji; Kusam, Saritha; Hollenback, David; Mahadevan, Sangeetha; Marchand, Bruno; Toteva, Maria; Breckenridge, David G; Trevaskis, James L; Bates, Jamie