日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combinations of an acetyl CoA carboxylase inhibitor with hepatic lipid modulating agents do not augment antifibrotic efficacy in preclinical models of NASH and fibrosis

在非酒精性脂肪性肝炎和纤维化的临床前模型中,乙酰辅酶A羧化酶抑制剂与肝脏脂质调节剂联合使用并不能增强抗纤维化疗效。

Vijayakumar, Archana; Okesli-Armlovich, Ayse; Wang, Ting; Olson, Isabel; Seung, Minji; Kusam, Saritha; Hollenback, David; Mahadevan, Sangeetha; Marchand, Bruno; Toteva, Maria; Breckenridge, David G; Trevaskis, James L; Bates, Jamie

Selonsertib Enhances Kidney Protection Beyond Standard of Care in a Hypertensive, Secondary Glomerulosclerosis CKD Model.

在高血压继发性肾小球硬化 CKD 模型中,Selonsertib 可增强肾脏保护作用,优于标准治疗

Badal Shawn S, Al Tuhaifi Tareq, Yu Ya-Fen, Lopez David, Plato Craig T, Joly Kristin, Breckenridge David G, Yang Hai-Chun, Liles John T, Fogo Agnes B

Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injury

凋亡信号调节激酶1抑制剂可预防对乙酰氨基酚引起的肝损伤

Xie, Yuchao; Ramachandran, Anup; Breckenridge, David G; Liles, John T; Lebofsky, Margitta; Farhood, Anwar; Jaeschke, Hartmut

Bcl-2 proteins EGL-1 and CED-9 do not regulate mitochondrial fission or fusion in Caenorhabditis elegans

Bcl-2蛋白EGL-1和CED-9不调控秀丽隐杆线虫的线粒体分裂或融合。

Breckenridge, David G; Kang, Byung-Ho; Xue, Ding