日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Assessment of antigen-specific T cell recall responses in non-human primates using a composite AIM assay

利用复合AIM检测评估非人灵长类动物体内抗原特异性T细胞记忆反应

Jan M Schmidt ,Mayuri Prasad ,Kenna Degner ,Rebecca Schiavo ,Allison Repic ,Lauren Little ,Laura Israel ,Feng Chen ,Regine Hansen ,Anette C Karle ,Kees Leenhouts ,Poul Sørensen ,Brian McIntosh ,Dominique Brees ,José M Carballido

Impact of pre-existing immunity on safety and biodistribution of a single AAV9 vectorintrathecal injection in cynomolgus monkeys.

既往免疫对食蟹猴单次鞘内注射 AAV9 载体的安全性和生物分布的影响。

Vono Maria, Rio Tony Del, Magdaleno Eduardo, Loll Nathalie R, Jarvis Philip, Walter Catherine, Kikkawa Rie, Mansfield Keith, McBlane Fraser, Sirivelu Madhu P, Ozsolak Fatih, Brees Dominique, Hudry Eloise, Rubic-Schneider Tina, Tukov Francis Fonyuy, Huang Guanrong

Patients with naproxen-induced liver injury display T-cell memory responses toward an oxidative (S)-O-desmethyl naproxen metabolite but not the acyl glucuronide

萘普生引起的肝损伤患者对萘普生的氧化代谢产物(S)-O-去甲基代谢物表现出T细胞记忆反应,但对酰基葡糖醛酸苷则无反应。

Thomson, Paul; Fragkas, Nik; Kafu, Laila M; Aithal, Guruprasad P; Lucena, M Isabel; Terracciano, Luigi; Meng, Xiaoli; Pirmohamed, Munir; Brees, Dominique; Kullak-Ublick, Gerd A; Odermatt, Alex; Hammond, Thomas; Kammüller, Michael; Naisbitt, Dean J

Digital quantitation of bridging fibrosis and septa reveals changes in natural history and treatment not seen with conventional histology

对桥接纤维化和间隔进行数字化定量分析,揭示了传统组织学无法观察到的自然病程和治疗变化。

Naoumov, Nikolai V; Kleiner, David E; Chng, Elaine; Brees, Dominique; Saravanan, Chandra; Ren, Yayun; Tai, Dean; Sanyal, Arun J

International consortium for innovation and quality: An industry perspective on the nonclinical and early clinical development of intravitreal drugs

国际创新与质量联盟:玻璃体内药物非临床和早期临床开发的行业视角

Pruimboom-Brees, Ingrid M; Gupta, Swati; Chemuturi, Nagendra; Booler, Helen S; Nimz, Erik; Ferrell Ramos, Meg; Caruso, Antonello; Maass, Katie F; Bantseev, Vladimir; Huang, Qihong; Choules, Mary P; Nussbaum, Jesse C; Kanodia, Jitendra; Thompson, Christopher; Durairaj, Chandrasekar

Therapeutic antibody glycosylation impacts antigen recognition and immunogenicity

治疗性抗体糖基化影响抗原识别和免疫原性

Babette Wolf, Mateusz Piksa, Isabelle Beley, Agnes Patoux, Thierry Besson, Valerie Cordier, Bernd Voedisch, Patrick Schindler, Daniela Stöllner, Ludovic Perrot, Stephan von Gunten, Dominique Brees, Michael Kammüller

TNF-α antagonists differentially induce TGF-β1-dependent resuscitation of dormant-like Mycobacterium tuberculosis

TNF-α 拮抗剂以差异方式诱导 TGF-β1 依赖的休眠型结核分枝杆菌复苏

Ainhoa Arbués, Dominique Brees, Salah-Dine Chibout, Todd Fox, Michael Kammüller, Damien Portevin

Peroxisomes as Modulators of Cellular Protein Thiol Oxidation: A New Model System

过氧化物酶体作为细胞蛋白质硫醇氧化的调节剂:一个新的模型系统

Celien Lismont, Marcus Nordgren, Chantal Brees, Bernard Knoops, Paul P Van Veldhoven, Marc Fransen

Coordinated regulation of transcription by CcpA and the Staphylococcus aureus two-component system HptRS.

CcpA 和金黄色葡萄球菌双组分系统 HptRS 对转录进行协调调控

Reed Joseph M, Olson Sean, Brees Danielle F, Griffin Caitlin E, Grove Ryan A, Davis Paul J, Kachman Stephen D, Adamec Jiri, Somerville Greg A

Inhibition of IL-17A by secukinumab shows no evidence of increased Mycobacterium tuberculosis infections

司库奇尤单抗对IL-17A的抑制作用并未显示结核分枝杆菌感染增加的证据

Kammüller, Michael; Tsai, Tsen-Fang; Griffiths, Christopher Em; Kapoor, Nidhi; Kolattukudy, Pappachan E; Brees, Dominique; Chibout, Salah-Dine; Safi, Jorge Jr; Fox, Todd