A rare variant in GPR156 associated with depression in a Mennonite pedigree causes habenula hyperactivity and stress sensitivity in mice
在门诺派家族中发现的一种与抑郁症相关的GPR156罕见变异会导致小鼠缰核过度活跃和应激敏感性。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2404754122
Miller, Bradley R; Gonzaga-Jauregui, Claudia; Brigatti, Karlla W; de Jong, Job; Breese, Robert S; Ko, Seung Yeon; Puffenberger, Erik G; Van Hout, Cristopher; Young, Millie; Luna, Victor M; Staples, Jeffrey; First, Michael B; Gregoire, Hilledna J; Dwork, Andrew J; Pefanis, Evangelos; McCarthy, Shane; Brydges, Susannah; Rojas, Jose; Ye, Bin; Stahl, Eli; Di Gioia, Silvio Alessandro; Hen, René; Elwood, Kevin; Rosoklija, Gorazd; Li, Dadong; Mellis, Scott; Carey, David; Croll, Susan D; Overton, John D; Macdonald, Lynn E; Economides, Aris N; Shuldiner, Alan R; Chuhma, Nao; Rayport, Stephen; Amin, Najaf; Kushner, Steven A; Alessandri-Haber, Nicole; Markx, Sander; Strauss, Kevin A
