日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hyperactivation of mTORC1 signaling mediates folliculin deficiency-induced pulmonary cyst formation in Birt-Hogg-Dubé syndrome

在Birt-Hogg-Dubé综合征中,mTORC1信号通路过度激活介导了滤泡蛋白缺乏引起的肺囊肿形成。

Cao, Ke; Chen, Hui; Chu, Ling; Wang, Hong-Jun; Zhang, Jianhua; Luo, Yongfeng; Chiu, Joanne; Khabibullin, Damir; Alesi, Nicola; Thornton, Matthew E; Grubbs, Brendan H; Ataya, Ali; Gupta, Nishant; McCormack, Francis X; Wikenheiser-Brokamp, Kathryn A; Henske, Elizabeth P; Shi, Wei

Integrative exome sequencing and machine learning identify MICB and interferon pathway genes as contributors to SSc risk

整合外显子组测序和机器学习技术发现,MICB 和干扰素通路基因是系统性硬化症风险的促成因素。

Ketkar, Shamika; Dai, Hongzheng; Burrage, Lindsay; Murdock, David; Dawson, Brian; Acosta-Herrera, Marialbert; Kerick, Martin; Martin, Javier; Wilhelm, Kevin; Asmussen, Jennifer Kay; Lichtarge, Olivier; Center, Regeneron Genetics; Assassi, Shervin; Mayes, Maureen D; Lee, Brendan H

Axial nephron fate switching demonstrates a plastic system tunable on demand.

轴向肾单位命运转换表明,这是一个可按需调节的可塑性系统

Achieng MaryAnne A, Schnell Jack, Fausto Connor C, Csipán Réka L, Koppitch Kari, Thornton Matthew E, Grubbs Brendan H, Lindström Nils O

RNA in Plasma Extracellular Vesicles of Adolescent Rhesus Macaques Reveal Immune, Bioenergetic, and Microbial Imprints of Early-Life Adversity: An Exploratory Analysis

青春期恒河猴血浆细胞外囊泡中的RNA揭示早期生活逆境的免疫、生物能量和微生物印记:一项探索性分析

Korobkova, Laura; Thornton, Matthew E; Collin, Matthew A; Morin, Elyse L; Aoued, Hadj; Sannigrahi, Soma; Bhinderwala, Nabeel; Garza, Kristie M; Siebert, Erin R; Walum, Hasse; Cabeen, Ryan P; Grubbs, Brendan H; Sanchez, Mar M; Dias, Brian G

Heterogeneous origins and functions of lung mesenchymal stromal cells

肺间充质基质细胞的异质性起源和功能

Peng, Danyi; Cao, Ke; Yang, Ruili; Luo, Yongfeng; Chen, Hui; Madala, Satish K; Thornton, Matthew E; Grubbs, Brendan H; Henske, Elizabeth P; Majka, Susan M; Shi, Wei

Multicellular tumor-stromal interactions recapitulate aspects of therapeutic response and human oncogenic signaling in a 3D disease model for H3K27M-altered DIPG.

在 H3K27M 改变的 DIPG 的 3D 疾病模型中,多细胞肿瘤-基质相互作用重现了治疗反应和人类致癌信号传导的某些方面。

Upreti Meenakshi, Petrosyan Astgik, Thornton Matthew E, Hovsepyan Anahit, Fernandez G Esteban, Koos David S, Byrum Stephanie D, Mackintosh Samuel G, Al-Husseini Jacob K, Porras Tania, Ha Joseph, Tackett Alan J, Zhang Miqin, Johal Malkiat S, Erdreich-Epstein Anat, Durham Susan, Krieger Mark D, Margol Ashley S, Grubbs Brendan H, Chambers Timothy C, Asgharzadeh Shahab, Moats Rex A, Chiarelli Peter A

Identification and characterization of early human photoreceptor states and cell-state-specific retinoblastoma-related features.

早期人类感光细胞状态的鉴定和表征以及细胞状态特异性视网膜母细胞瘤相关特征

Shayler Dominic W H, Stachelek Kevin, Cambier Linda, Lee Sunhye, Bai Jinlun, Bhat Bhavana, Reid Mark W, Weisenberger Daniel J, Aparicio Jennifer G, Kim Yeha, Singh Mitali, Bay Maxwell, Thornton Matthew E, Doyle Eamon K, Fouladian Zachary, Erberich Stephan G, Grubbs Brendan H, Bonaguidi Michael A, Craft Cheryl Mae, Singh Hardeep P, Cobrinik David

C-terminal frameshift variants in GPKOW are associated with a multisystemic X-linked disorder

GPKOW基因C端移码变异与一种多系统性X连锁疾病相关。

Mok, Jung-Wan; Mackay, Laura; Blazo, Maria; Mizerik, Elizabeth; Gecz, Jozef; Carroll, Renee; Nizon, Mathilde; Rondeau, Sophie; Joubert, Madeleine; Cuinat, Silvestre; Deb, Wallid; Valle Sirias, Fernanda; Weisz-Hubshman, Monika; Ketkar, Shamika; Polak, Urszula; Tran, Alyssa A; Kearney, Debra; Hanchard, Neil A; Kanca, Oguz; Wangler, Michael F; Bellen, Hugo J; Lee, Brendan H; Yamamoto, Shinya; Machol, Keren

Non-invasive neuromodulation for the treatment of drug-resistant epilepsy: Protocol for a systematic review and meta-analysis investigating efficacy, safety, and optimal stimulation parameters

非侵入性神经调控治疗药物难治性癫痫:一项系统评价和荟萃分析方案,旨在探讨其疗效、安全性和最佳刺激参数

Premaratne, Sayumi; Zoghi, Maryam; Antonic-Baker, Ana; Chen, Zhibin; Chen, Leo; Hamer, Ryan; Major, Brendan; H X Thomas, Elizabeth; Kwan, Patrick; J O'Brien, Terence; N Lundstrom, Brian; D Simpson, Hugh

Perceived Stress During Late Pregnancy and Infant Body Composition at 1 Month

孕晚期感知压力与婴儿出生后1个月的身体成分

Yang, Xiaoran; Eckel, Sandrah P; Maldonado, Luis E; Yang, Tingyu; Chen, Xinci; Vigil, Mario; Toledo-Corral, Claudia M; Dunton, Genevieve F; Grubbs, Brendan H; Al-Marayati, Laila; Lerner, Deborah; Lurvey, Nathana; Habre, Rima; Farzan, Shohreh F; Bastain, Theresa M; Breton, Carrie