日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A companion to the preclinical common data elements for genomics, transcriptomics, and epigenomics data in rodent epilepsy models. A report of the TASK3-WG4 omics working group of the ILAE/AES joint translational TASK force

啮齿动物癫痫模型基因组学、转录组学和表观基因组学数据的临床前通用数据元素指南。国际抗癫痫联盟/美国癫痫学会联合转化工作组TASK3-WG4组学工作组的报告。

van Vliet, Erwin A; Hildebrand, Michael S; Mills, James D; Brennan, Gary P; Eid, Tore; Masino, Susan A; Whittemore, Vicky; Bindila, Laura; Wang, Kevin K; Patel, Manisha; Perucca, Piero; Reid, Christopher A

A companion to the preclinical common data elements for proteomics, lipidomics, and metabolomics data in rodent epilepsy models. A report of the TASK3-WG4 omics working group of the ILAE/AES joint translational TASK force

啮齿动物癫痫模型中蛋白质组学、脂质组学和代谢组学数据的临床前通用数据元素指南。国际抗癫痫联盟/美国癫痫学会联合转化工作组TASK3-WG4组学工作组的报告。

Bindila, Laura; Eid, Tore; Mills, James D; Hildebrand, Michael S; Brennan, Gary P; Masino, Susan A; Whittemore, Vicky; Perucca, Piero; Reid, Christopher A; Patel, Manisha; Wang, Kevin K; van Vliet, Erwin A

Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy.

实验性颞叶癫痫中循环microRNA生物标志物的脑细胞特异性起源

Brindley Elizabeth, Heiland Mona, Mooney Catherine, Diviney Mairead, Mamad Omar, Hill Thomas D M, Yan Yan, Venø Morten T, Reschke Cristina R, Batool Aasia, Langa Elena, Sanz-Rodriguez Amaya, Heller Janosch P, Morris Gareth, Conboy Karen, Kjems Jørgen, Brennan Gary P, Henshall David C

Systemic delivery of antagomirs during blood-brain barrier disruption is disease-modifying in experimental epilepsy

在血脑屏障破坏期间全身性递送抗癫痫药物可改善实验性癫痫的病情。

Reschke, Cristina R; Silva, Luiz F A; Vangoor, Vamshidhar R; Rosso, Massimo; David, Bastian; Cavanagh, Brenton L; Connolly, Niamh M C; Brennan, Gary P; Sanz-Rodriguez, Amaya; Mooney, Catherine; Batool, Aasia; Greene, Chris; Brennan, Marian; Conroy, Ronan M; Rüber, Theodor; Prehn, Jochen H M; Campbell, Matthew; Pasterkamp, R Jeroen; Henshall, David C

CHD2-Related CNS Pathologies

CHD2相关中枢神经系统病理

Wilson, Marc-Michel; Henshall, David C; Byrne, Susan M; Brennan, Gary P

Regulatory Mechanisms of the RNA Modification m(6)A and Significance in Brain Function in Health and Disease

RNA修饰m(6)A的调控机制及其在健康和疾病状态下脑功能中的意义

Mathoux, Justine; Henshall, David C; Brennan, Gary P

Multiple Disruptions of Glial-Neuronal Networks in Epileptogenesis That Follows Prolonged Febrile Seizures

持续性热性惊厥后癫痫发生过程中神经胶质-神经元网络的多重紊乱

Brennan, Gary P; Garcia-Curran, Megan M; Patterson, Katelin P; Luo, Renhao; Baram, Tallie Z

Genetic deletion of microRNA-22 blunts the inflammatory transcriptional response to status epilepticus and exacerbates epilepsy in mice

基因敲除microRNA-22会减弱小鼠癫痫持续状态的炎症转录反应,并加剧癫痫症状。

Almeida Silva, Luiz F; Reschke, Cristina R; Nguyen, Ngoc T; Langa, Elena; Sanz-Rodriguez, Amaya; Gerbatin, Rogerio R; Temp, Fernanda R; de Freitas, Mayara L; Conroy, Ronan M; Brennan, Gary P; Engel, Tobias; Henshall, David C

Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy

双中心、双平台microRNA谱分析鉴定成人颞叶癫痫的潜在血浆生物标志物

Raoof, Rana; Bauer, Sebastian; El Naggar, Hany; Connolly, Niamh M C; Brennan, Gary P; Brindley, Elizabeth; Hill, Thomas; McArdle, Hazel; Spain, Elaine; Forster, Robert J; Prehn, Jochen H M; Hamer, Hajo; Delanty, Norman; Rosenow, Felix; Mooney, Catherine; Henshall, David C

Spared CA1 pyramidal neuron function and hippocampal performance following antisense knockdown of microRNA-134

反义敲低microRNA-134后,CA1锥体神经元功能和海马体功能得以保留

Morris, Gareth; Brennan, Gary P; Reschke, Cristina R; Henshall, David C; Schorge, Stephanie