日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mitochondrial cardiolipin sequestration of caspofungin underlies Cryptococcus neoformans inherent resistance and may contribute to cardiotoxicity

线粒体心磷脂螯合卡泊芬净是新型隐球菌固有耐药性的基础,并可能导致心脏毒性。

Loksztejn, Anna K; Upadhya, Rajendra; Caro, Eduardo A; Gooden, David M; Yona, Adi; Ellis, Porter K; Fridman, Micha; Schumacher, Maria A; Brennan, Richard G; Donlin, Maureen J; Lodge, Jennifer K

Inhibitors of trehalose-6-phosphate synthase activity in fungal pathogens compromise thermal tolerance pathways

真菌病原体中海藻糖-6-磷酸合成酶活性的抑制剂会损害其耐热途径。

Miao, Yi; Yadav, Vikas; Shadrick, William; Liu, Jiuyu; Jenner, Alexander R; Nichols, Connie B; Gee, Clifford; Schäfer, Martin; Tenor, Jennifer L; Perfect, John R; Lee, Richard E; Brennan, Richard G; Washington, Erica J

Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR

激素类固醇通过与MtrR结合,诱导淋病奈瑟菌产生多药耐药性和应激反应基因。

Hooks, Grace M; Ayala, Julio C; Holley, Concerta L; Dhulipala, Vijaya; Beggs, Grace A; Perfect, John R; Schumacher, Maria A; Shafer, William M; Brennan, Richard G

How c-di-GMP controls progression through the Streptomyces life cycle

c-di-GMP如何控制链霉菌生命周期的进程

Gallagher, Kelley A; Tschowri, Natalia; Brennan, Richard G; Schumacher, Maria A; Buttner, Mark J

Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans : a target for novel antifungals

来自新型隐球菌的海藻糖-6-磷酸合成酶Tps1的结构:新型抗真菌药物的靶点

Washington, Erica J; Zhou, Ye; Hsu, Allen L; Petrovich, Matthew; Tenor, Jennifer L; Toffaletti, Dena L; Guan, Ziqiang; Perfect, John R; Borgnia, Mario J; Bartesaghi, Alberto; Brennan, Richard G

Hormonal steroids bind the Neisseria gonorrhoeae multidrug resistance regulator, MtrR, to induce a multidrug binding efflux pump and stress-response sigma factor

激素类固醇与淋病奈瑟菌多药耐药调节因子 MtrR 结合,诱导多药结合外排泵和应激反应 σ 因子的表达。

Hooks, Grace M; Ayala, Julio C; Beggs, Grace A; Perfect, John R; Schumacher, Maria A; Shafer, William M; Brennan, Richard G

P042 Identification, clinical profile, antifungal susceptibility pattern of candida auris from a tertiary care center in india

P042 印度一家三级医疗中心耳念珠菌的鉴定、临床特征和抗真菌药物敏感性模式

Thammahong, Arsa; Puttikamonkul, Srisombat; Perfect, John R; Brennan, Richard G; Cramer, Robert A; Danni, Mary Kiran; Kindo, Anupma Jyoti; Jayalakshmi, J; Renuka, M K

Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations

淋病奈瑟菌MtrR操纵子复合物的结构揭示了DNA识别和抗生素耐药性相关临床突变的分子机制

Beggs, Grace A; Ayala, Julio C; Kavanaugh, Logan G; Read, Timothy D; Hooks, Grace M; Schumacher, Maria A; Shafer, William M; Brennan, Richard G

Evolution of a σ-(c-di-GMP)-anti-σ switch

σ-(c-di-GMP)-anti-σ开关的进化

Schumacher, Maria A; Gallagher, Kelley A; Holmes, Neil A; Chandra, Govind; Henderson, Max; Kysela, David T; Brennan, Richard G; Buttner, Mark J

When is a transcription factor a NAP?

转录因子何时会成为NAP?

Dorman, Charles J; Schumacher, Maria A; Bush, Matthew J; Brennan, Richard G; Buttner, Mark J