MEK-SHP2 inhibition prevents tibial pseudarthrosis caused by NF1 loss in Schwann cells and skeletal stem/progenitor cells
MEK-SHP2抑制剂可预防由雪旺细胞和骨骼干/祖细胞中NF1缺失引起的胫骨假关节形成。
期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.adj1597
Perrin, Simon; Protic, Sanela; Bretegnier, Vincent; Laurendeau, Ingrid; de Lageneste, Oriane Duchamp; Panara, Nicolas; Ruckebusch, Odile; Luka, Marine; Masson, Cécile; Maillard, Théodora; Coulpier, Fanny; Pannier, Stéphanie; Wicart, Philippe; Hadj-Rabia, Smail; Radomska, Katarzyna J; Zarhrate, Mohammed; Ménager, Mickael; Vidaud, Dominique; Topilko, Piotr; Parfait, Béatrice; Colnot, Céline
