日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Successes and Challenges in Clinical Trial Recruitment: The Experience of a New Study Team

临床试验招募的成功与挑战:一个新研究团队的经验

Hung, Man; Mohajeri, Amir; Almpani, Konstantinia; Carberry, Gabriel; Wisniewski, John F; Janes, Kade; Janes, Brooklyn; Hardy, Chase; Zakeri, Golnoush; Raymond, Ben; Trinh, Heather; Bretner, Jordan; Cheever, Val J; Garibyan, Rafael; Bachstein, Perry; Licari, Frank W

Synthesis of Novel Acyl Derivatives of 3-(4,5,6,7-Tetrabromo-1 H-benzimidazol-1-yl)propan-1-ols-Intracellular TBBi-Based CK2 Inhibitors with Proapoptotic Properties

3-(4,5,6,7-四溴-1H-苯并咪唑-1-基)丙-1-醇新型酰基衍生物的合成-具有促凋亡特性的细胞内 TBBi 基 CK2 抑制剂

Konrad Chojnacki, Patrycja Wińska, Olena Karatsai, Mirosława Koronkiewicz, Małgorzata Milner-Krawczyk, Monika Wielechowska, Maria Jolanta Rędowicz, Maria Bretner, Paweł Borowiecki

Diacritic Binding of an Indenoindole Inhibitor by CK2α Paralogs Explored by a Reliable Path to Atomic Resolution CK2α' Structures

通过可靠的原子分辨率CK2α'结构解析方法探索CK2α旁系同源物对茚并吲哚抑制剂的重音符号结合

Lindenblatt, Dirk; Nickelsen, Anna; Applegate, Violetta M; Hochscherf, Jennifer; Witulski, Benedict; Bouaziz, Zouhair; Marminon, Christelle; Bretner, Maria; Le Borgne, Marc; Jose, Joachim; Niefind, Karsten

Synthesis of polybrominated benzimidazole and benzotriazole derivatives containing a tetrazole ring and their cytotoxic activity

含四唑环的多溴苯并咪唑和苯并三唑衍生物的合成及其细胞毒活性

Edyta Łukowska-Chojnacka, Patrycja Wińska, Monika Wielechowska, Maria Bretner

Treatment of cultured human astrocytes and vascular endothelial cells with protein kinase CK2 inhibitors induces early changes in cell shape and cytoskeleton

用蛋白激酶CK2抑制剂处理培养的人类星形胶质细胞和血管内皮细胞,可诱导细胞形状和细胞骨架的早期变化。

Kramerov, A A; Golub, A G; Bdzhola, V G; Yarmoluk, S M; Ahmed, K; Bretner, M; Ljubimov, A V

Unbiased functional proteomics strategy for protein kinase inhibitor validation and identification of bona fide protein kinase substrates: application to identification of EEF1D as a substrate for CK2

无偏倚功能蛋白质组学策略用于蛋白激酶抑制剂验证和鉴定真正的蛋白激酶底物:应用于鉴定EEF1D作为CK2的底物

Gyenis, Laszlo; Duncan, James S; Turowec, Jacob P; Bretner, Maria; Litchfield, David W

Inhibition of protein kinase CK2 suppresses angiogenesis and hematopoietic stem cell recruitment to retinal neovascularization sites

抑制蛋白激酶CK2可抑制血管生成和造血干细胞向视网膜新生血管部位的募集。

Kramerov, A A; Saghizadeh, M; Caballero, S; Shaw, L C; Li Calzi, S; Bretner, M; Montenarh, M; Pinna, L A; Grant, M B; Ljubimov, A V

Purification and characterization of West Nile virus nucleoside triphosphatase (NTPase)/helicase: evidence for dissociation of the NTPase and helicase activities of the enzyme

西尼罗病毒核苷三磷酸酶(NTPase)/解旋酶的纯化和表征:该酶的NTPase活性和解旋酶活性分离的证据

Borowski, P; Niebuhr, A; Mueller, O; Bretner, M; Felczak, K; Kulikowski, T; Schmitz, H