日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Biophysical mapping of TREM2-ligand interactions reveals shared surfaces for engagement of multiple Alzheimer's disease ligands

TREM2-配体相互作用的生物物理映射揭示了多种阿尔茨海默病配体结合的共同表面

Greven, Jessica A; Wydra, Joshua R; Greer, Rory A; Zhi, Cynthia; Price, David A; Svoboda, Jordyn D; Camitta, Christopher L M; Washington, Mya; Leung, Daisy W; Song, Yuhua; Alexander-Brett, Jen; Brett, Tom J

Modulation of TMEM16B channel activity by the calcium-activated chloride channel regulator 4 (CLCA4) in human cells

钙激活氯离子通道调节因子4 (CLCA4) 对人细胞中TMEM16B通道活性的调节

Sala-Rabanal, Monica; Yurtsever, Zeynep; Berry, Kayla N; McClenaghan, Conor; Foy, Alyssa J; Hanson, Alex; Steinberg, Deborah F; Greven, Jessica A; Kluender, Colin E; Alexander-Brett, Jennifer M; Nichols, Colin G; Brett, Tom J

Structural and Biophysical Analysis of the CLCA1 VWA Domain Suggests Mode of TMEM16A Engagement.

CLCA1 VWA 结构域的结构和生物物理分析揭示了 TMEM16A 的相互作用模式

Berry Kayla N, Brett Tom J

The Ebola Viral Protein 35 N-Terminus Is a Parallel Tetramer

埃博拉病毒蛋白35的N端是一个平行四聚体。

Chanthamontri, Chamnongsak Ken; Jordan, David S; Wang, Wenjie; Wu, Chao; Lin, Yanchun; Brett, Tom J; Gross, Michael L; Leung, Daisy W

Data publication with the structural biology data grid supports live analysis

利用结构生物学数据网格发布数据支持实时分析

Meyer, Peter A; Socias, Stephanie; Key, Jason; Ransey, Elizabeth; Tjon, Emily C; Buschiazzo, Alejandro; Lei, Ming; Botka, Chris; Withrow, James; Neau, David; Rajashankar, Kanagalaghatta; Anderson, Karen S; Baxter, Richard H; Blacklow, Stephen C; Boggon, Titus J; Bonvin, Alexandre M J J; Borek, Dominika; Brett, Tom J; Caflisch, Amedeo; Chang, Chung-I; Chazin, Walter J; Corbett, Kevin D; Cosgrove, Michael S; Crosson, Sean; Dhe-Paganon, Sirano; Di Cera, Enrico; Drennan, Catherine L; Eck, Michael J; Eichman, Brandt F; Fan, Qing R; Ferré-D'Amaré, Adrian R; Fromme, J Christopher; Garcia, K Christopher; Gaudet, Rachelle; Gong, Peng; Harrison, Stephen C; Heldwein, Ekaterina E; Jia, Zongchao; Keenan, Robert J; Kruse, Andrew C; Kvansakul, Marc; McLellan, Jason S; Modis, Yorgo; Nam, Yunsun; Otwinowski, Zbyszek; Pai, Emil F; Pereira, Pedro José Barbosa; Petosa, Carlo; Raman, C S; Rapoport, Tom A; Roll-Mecak, Antonina; Rosen, Michael K; Rudenko, Gabby; Schlessinger, Joseph; Schwartz, Thomas U; Shamoo, Yousif; Sondermann, Holger; Tao, Yizhi J; Tolia, Niraj H; Tsodikov, Oleg V; Westover, Kenneth D; Wu, Hao; Foster, Ian; Fraser, James S; Maia, Filipe R N C; Gonen, Tamir; Kirchhausen, Tom; Diederichs, Kay; Crosas, Mercè; Sliz, Piotr

CLCA1 and TMEM16A: the link towards a potential cure for airway diseases

CLCA1 和 TMEM16A:通往潜在治愈气道疾病的纽带

Brett, Tom J

The crystal structure of phosphorylated MAPK13 reveals common structural features and differences in p38 MAPK family activation

磷酸化MAPK13的晶体结构揭示了p38 MAPK家族激活的共同结构特征和差异

Yurtsever, Zeynep; Scheaffer, Suzanne M; Romero, Arthur G; Holtzman, Michael J; Brett, Tom J

Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1

埃博拉病毒VP24靶向核转运蛋白α5上的独特NLS结合位点,从而选择性地与磷酸化STAT1的核输入竞争。

Xu, Wei; Edwards, Megan R; Borek, Dominika M; Feagins, Alicia R; Mittal, Anuradha; Alinger, Joshua B; Berry, Kayla N; Yen, Benjamin; Hamilton, Jennifer; Brett, Tom J; Pappu, Rohit V; Leung, Daisy W; Basler, Christopher F; Amarasinghe, Gaya K

IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.

MAPK13抑制剂可减弱IL-13诱导的气道粘液产生

Alevy Yael G, Patel Anand C, Romero Arthur G, Patel Dhara A, Tucker Jennifer, Roswit William T, Miller Chantel A, Heier Richard F, Byers Derek E, Brett Tom J, Holtzman Michael J

The role of CLCA proteins in inflammatory airway disease

CLCA蛋白在炎症性气道疾病中的作用

Patel, Anand C; Brett, Tom J; Holtzman, Michael J